(Q51629833)

8 April 2018

title

Effect on antibody and T-cell responses of mixing five GMP-produced DNA plasmids and administration with plasmid expressing GM-CSF. (English)

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14

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Stephen L. Hoffman

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object named as

Hoffman SL

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11

Druilhe P

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author name string

Sedegah M

1

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Charoenvit Y

2

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Aguiar J

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Sacci J

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Hedstrom R

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Kumar S

6

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Belmonte A

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Lanar DE

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Jones TR

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Abot E

10

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Corradin G

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Epstein JE

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Carucci DJ

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publication date

1 November 2004

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published in

Genes and Immunity

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volume

5

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issue

7

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page(s)

553-561

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https://scigraph.springernature.com/pub.10.1038/sj.gene.6364125

exact match

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Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity

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Enhancement of the immune response in rabbits to a malaria DNA vaccine by immunization with a needle-free jet device

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Protection of Aotus monkeys by Plasmodium falciparum EBA-175 region II DNA prime-protein boost immunization regimen

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Absence of antigenic competition in Aotus monkeys immunized with Plasmodium falciparum DNA vaccines delivered as a mixture

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Multistage multiantigen heterologous prime boost vaccine for Plasmodium knowlesi malaria provides partial protection in rhesus macaques

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Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers

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Long synthetic peptides encompassing the Plasmodium falciparum LSA3 are the target of human B and T cells and are potent inducers of B helper, T helper and cytolytic T cell responses in mice

21 January 2018

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Recognition of synthetic polypeptides corresponding to the N- and C-terminal fragments of Plasmodium falciparum Exp-1 by T-cells and plasma from human donors from African endemic areas

21 January 2018

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Reduced immunogenicity of DNA vaccine plasmids in mixtures

21 January 2018

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A DNA vaccine encoding the 42 kDa C-terminus of merozoite surface protein 1 of Plasmodium falciparum induces antibody, interferon-gamma and cytotoxic T cell responses in rhesus monkeys: immuno-stimulatory effects of granulocyte macrophage-colony sti

21 January 2018

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Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3.

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A Plasmodium falciparum malaria vaccine candidate which contains epitopes from the circumsporozoite protein and a blood stage antigen, 5.1.

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Induction of murine cytotoxic T lymphocytes against Plasmodium falciparum sporozoite surface protein 2.

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Quantification of antigen specific CD8+ T cells using an ELISPOT assay.

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Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine

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21 January 2018

Identifiers

DOI

10.1038/SJ.GENE.6364125

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8 April 2018

Dimensions Publication ID

0 references

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8 April 2018