(Q51722146)

10 April 2018

title

Development of a 7-day, 96-well Caco-2 permeability assay with high-throughput direct UV compound analysis. (English)

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10 April 2018

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Jochem Alsenz

1

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10 April 2018

E Haenel

series ordinal

2

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10 April 2018

publication date

1 December 2003

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10 April 2018

published in

Pharmaceutical Research

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10 April 2018

volume

20

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10 April 2018

page(s)

1961-1969

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10 April 2018

issue

12

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10 April 2018

Evaluation of Biocoat intestinal epithelium differentiation environment (3-day cultured Caco-2 cells) as an absorption screening model with improved productivity

cites work

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12 December 2020

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

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12 December 2020

Absorption classification of oral drugs based on molecular surface properties

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12 December 2020

Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach

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12 December 2020

Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs

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12 December 2020

The role of surfactants in the reversal of active transport mediated by multidrug resistance proteins

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12 December 2020

Improvement of megakaryocytic progenitor culture for toxicological investigations.

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12 December 2020

Evaluation of an accelerated Caco-2 cell permeability model.

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12 December 2020

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

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12 December 2020

New and better protocols for a short-term Caco-2 cell culture system

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12 December 2020

The influence of caprate on rectal absorption of phenoxymethylpenicillin: experience from an in-vivo perfusion in humans

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12 December 2020

Determination of in vitro permeability of drug candidates through a caco-2 cell monolayer by liquid chromatography/tandem mass spectrometry

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12 December 2020

High-throughput caco-2 cell permeability screening by cassette dosing and sample pooling approaches using direct injection/on-line guard cartridge extraction/tandem mass spectrometry

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12 December 2020

Development of a more rapid, reduced serum culture system for Caco-2 monolayers and application to the biopharmaceutics classification system

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12 December 2020

Intestinal absorption screening of mixtures from combinatorial libraries in the Caco-2 model

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12 December 2020

Active apical secretory efflux of the HIV protease inhibitors saquinavir and ritonavir in Caco-2 cell monolayers

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12 December 2020

Optimizing Caco-2 cell monolayers to increase throughput in drug intestinal absorption analysis

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12 December 2020

The effect of amiloride on the in vivo effective permeability of amoxicillin in human jejunum: experience from a regional perfusion technique

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12 December 2020

Automated absorption assessment using Caco-2 cells cultured on both sides of polycarbonate membranes

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12 December 2020

Human jejunal permeability of two polar drugs: cimetidine and ranitidine

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12 December 2020

Caco-2 monolayers in experimental and theoretical predictions of drug transport

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12 December 2020

MDCK (Madin-Darby canine kidney) cells: A tool for membrane permeability screening

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12 December 2020

Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells

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12 December 2020

10.1023/B:PHAM.0000008043.71001.43

Identifiers

DOI

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10 April 2018

PubMed ID

14725360

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10 April 2018