(Q51737021)

English

High-Dose Deferoxamine Treatment Disrupts Intracellular Iron Homeostasis, Reduces Growth, and Induces Apoptosis in Metastatic and Nonmetastatic Breast Cancer Cell Lines.

scientific article published in January 2018

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

High-Dose Deferoxamine Treatment Disrupts Intracellular Iron Homeostasis, Reduces Growth, and Induces Apoptosis in Metastatic and Nonmetastatic Breast Cancer Cell Lines. (English)

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

1 reference

based on heuristic

inferred from title

author name string

Khuloud Bajbouj

1

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

Jasmin Shafarin

2

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

Mawieh Hamad

3

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

publication date

1 January 2018

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

Technology in Cancer Research and Treatment

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

17

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

1533033818764470

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5865460/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Contrasting intra- and extracellular distribution of catalytic ferrous iron in ovalbumin-induced peritonitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Deferoxamine-induced increase in the intracellular iron levels in highly aggressive breast cancer cells leads to increased cell migration by enhancing TNF-α-dependent NF-κB signaling and TGF-β signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Modulation of iron metabolism by iron chelation regulates intracellular calcium and increases sensitivity to doxorubicin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Defective autophagosome formation in p53-null colorectal cancer reinforces crocin-induced apoptosis

1 reference

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22 May 2018

Systemic and tumor level iron regulation in men with colorectal cancer: a case control study

1 reference

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22 May 2018

Regulation of cellular iron metabolism and its implications in lung cancer progression

1 reference

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22 May 2018

Cancer cells with irons in the fire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function

1 reference

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22 May 2018

A probable risk factor of female breast cancer: study on benign and malignant breast tissue samples

1 reference

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22 May 2018

Iron chelation therapy in myelodysplastic syndromes: where do we stand?

1 reference

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22 May 2018

Cellular iron metabolism in prognosis and therapy of breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Intestinal iron homeostasis and colon tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Iron chelation in the treatment of cancer: a new role for deferasirox?

1 reference

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22 May 2018

Iron and cancer: more ore to be mined

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Lipocalin 2 is a novel regulator of angiogenesis in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Iron chelators with topoisomerase-inhibitory activity and their anticancer applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Essential but toxic: controlling the flux of iron in the body.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

The hazards of iron loading

1 reference

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22 May 2018

Ferroportin and iron regulation in breast cancer progression and prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

1 reference

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22 May 2018

Dietary and stored iron as predictors of breast cancer risk: A nested case-control study in Shanghai

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Lipocalin 2 promotes breast cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Does iron have a role in breast cancer?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression

1 reference

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22 May 2018

Does excess iron play a role in breast carcinogenesis? An unresolved hypothesis

1 reference

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22 May 2018

Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Intracellular labile iron pools as direct targets of iron chelators: a fluorescence study of chelator action in living cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

22 May 2018

Ferritin expression modulates cell cycle dynamics and cell responsiveness to H-ras-induced growth via expansion of the labile iron pool

1 reference

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22 May 2018

Role of ferritin in the control of the labile iron pool in murine erythroleukemia cells

1 reference

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22 May 2018

Inhibitory Activity of Iron Chelators ATA and DFO on MCF-7 Breast Cancer Cells and Phosphatases PTP1B and SHP2.

1 reference

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14 August 2018

Iron chelation therapy with deferasirox induced complete remission in a patient with chemotherapy-resistant acute monocytic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

14 August 2018

Role of ferritin alterations in human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5865460

14 August 2018

Flow cytometry measurement of the labile iron pool in human hematopoietic cells

1 reference

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14 August 2018

Levels of zinc, selenium, calcium, and iron in benign breast tissue and risk of subsequent breast cancer

1 reference

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14 August 2018

Differing sensitivity of tumor cells to apoptosis induced by iron deprivation in vitro

1 reference

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14 August 2018

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

1 reference

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29 September 2018

Ferritin as an independent mortality predictor in patients with pancreas cancer. Results of a pilot study

1 reference

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30 November 2018

Repression of ferritin expression increases the labile iron pool, oxidative stress, and short-term growth of human erythroleukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29562821

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1 reference

https://pubmed.ncbi.nlm.nih.gov/29562821

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1177/1533033818764470

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 April 2018

http://europepmc.org/abstract/PMC/5865460

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