(Q51744820)

http://europepmc.org/abstract/MED/29501973

11 April 2018

title

Safety and efficacy of the bumped kinase inhibitor BKI-1553 in pregnant sheep experimentally infected with Neospora caninum tachyzoites. (English)

1 reference

http://europepmc.org/abstract/MED/29501973

11 April 2018

main subject

Neospora caninum

0 references

experimental infection

1 reference

inferred from title

author

Javier Regidor Cerrillo

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Ignacio Ferre

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

M Re

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

Enrique Tabanera De Lucio

5 June 2020

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Julio Benavides

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Pablo Castaño

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Grant R Whitman

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Luis Miguel Ortega-Mora

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Roberto Sánchez-Sánchez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Patricia Vázquez

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Luis Miguel Ferrer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Javier Blanco-Murcia

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Manuel Pizarro Díaz

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Marta González-Huecas

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Paula García-Lunar

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Andrew Hemphill

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Matthew A Hulverson

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Kasey L Rivas

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Ryan Choi

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Kayode K Ojo

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Lynn K Barrett

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Wesley C Van Voorhis

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

publication date

1 March 2018

1 reference

http://europepmc.org/abstract/MED/29501973

11 April 2018

published in

International Journal for Parasitology: Drugs and Drug Resistance

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

112-124

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and the naphthoquinone buparvaquone against congenital toxoplasmosis.

5 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Two Novel Calcium-Dependent Protein Kinase 1 Inhibitors Interfere with Vertical Transmission in Mice Infected with Neospora caninum Tachyzoites.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Extended-spectrum antiprotozoal bumped kinase inhibitors: A review

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for Cryptosporidiosis.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Foetal death in naive heifers inoculated with Neospora caninum isolate Nc-Spain7 at 110 days of pregnancy

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

In Vitro and in Vivo Effects of Nitrofurantoin on Experimental Toxoplasmosis

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Experimental caprine neosporosis: the influence of gestational stage on the outcome of infection.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Systemic and local immune responses in sheep after Neospora caninum experimental infection at early, mid and late gestation.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Approaches for the vaccination and treatment of Neospora caninum infections in mice and ruminant models

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

In Vitro and In Vivo Effects of the Bumped Kinase Inhibitor 1294 in the Related Cyst-Forming Apicomplexans Toxoplasma gondii and Neospora caninum

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Study on the use of toltrazuril to eliminate Neospora caninum in congenitally infected lambs born from experimentally infected ewes.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Influence of the gestational stage on the clinical course, lesional development and parasite distribution in experimental ovine neosporosis

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Neospora caninum infection as a cause of reproductive failure in a sheep flock

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Bumped kinase inhibitor 1294 treats established Toxoplasma gondii infection.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Neospora caninum calcium-dependent protein kinase 1 is an effective drug target for neosporosis therapy

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Neospora caninum infection during early pregnancy in cattle: how the isolate influences infection dynamics, clinical outcome and peripheral and local immune responses

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Recent results in protein kinase inhibition for tropical diseases

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Application of quantitative real-time polymerase chain reaction for the diagnosis of toxoplasmosis and enzootic abortion of ewes

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

A role for xanthine oxidase in the control of fetal cardiovascular function in late gestation sheep.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Occurrence of Neospora caninum and Toxoplasma gondii infections in ovine and caprine abortions.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Neosporosis in animals--the last five years

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Drug target identification in intracellular and extracellular protozoan parasites

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Discovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondii

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Monensin use against Neospora caninum challenge in dairy cattle.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Influence of Neospora caninum intra-specific variability in the outcome of infection in a pregnant BALB/c mouse model

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Endogenous and exogenous transplacental transmission of Neospora caninum - how the route of transmission impacts on epidemiology and control of disease.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Dose-titration challenge of young pregnant sheep with Neospora caninum tachyzoites.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Toxoplasmosis in sheep--the last 20 years

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Isolation and genetic characterization of Neospora caninum from asymptomatic calves in Spain.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

The host-parasite relationship in pregnant cattle infected with Neospora caninum

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Efficacy, Pharmacokinetics, and Metabolism of Tetrahydroquinoline Inhibitors of Plasmodium falciparum Protein Farnesyltransferase

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Epidemiology and control of neosporosis and Neospora caninum

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Financial analysis of various strategies for the control of Neospora caninum in dairy cattle in Switzerland.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Simulating the impact of four control strategies on the population dynamics of Neospora caninum infection in Swiss dairy cattle.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Comparison of Neospora caninum distribution, parasite loads and lesions between epidemic and endemic bovine abortion cases.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Humoral immune reaction of newborn calves congenitally infected with Neospora caninum and experimentally treated with toltrazuril.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Placental pathology associated with fetal death in cattle inoculated with Neospora caninum by two different routes in early pregnancy

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

An explorative study to assess the efficacy of toltrazuril-sulfone (ponazuril) in calves experimentally infected with Neospora caninum

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Immune regulation during pregnancy and host-pathogen interactions in infectious abortion

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Quantitative detection of Neospora caninum in bovine aborted fetuses and experimentally infected mice by real-time PCR

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Toxoplasma gondii attachment to host cells is regulated by a calmodulin-like domain protein kinase

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Protozoan infections (Toxoplasma gondii, Neospora caninum and Sarcocystis spp.) in sheep and goats: recent advances.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

The pathogenesis of experimental neosporosis in pregnant sheep.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Maternal-fetal calcium and bone metabolism during pregnancy, puerperium, and lactation

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Experimental neosporosis in pregnant ewes and their offspring

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Decoquinate and the control of experimental ovine toxoplasmosis

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Assessment of the Hematopoietic System In Ruminants

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Protection against abortion linked to gamma interferon production in pregnant dairy cows naturally infected with Neospora caninum

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6114101

Further studies in the use of monensin in the control of experimental ovine toxoplasmosis

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29501973

12 December 2020

inferred from PubMed ID database lookup

Influence of age and purpose for testing on the cut-off selection of serological methods in bovine neosporosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29501973

12 December 2020

inferred from PubMed ID database lookup

Effects of seasonal and physiological variations on the serum chemistry, vitamins and thyroid hormone concentrations in sheep

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29501973

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.IJPDDR.2018.02.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29501973%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference