(Q36368024)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693272%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693272%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

0 references

22

1 reference

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3 March 2020

Marilyn Parsons

23

1 reference

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3 March 2020

17

Wim G J Hol

1 reference

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3 March 2020

author name string

Wenlin Huang

1

1 reference

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3 March 2020

Kayode K Ojo

2

1 reference

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3 March 2020

Zhongsheng Zhang

3

1 reference

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3 March 2020

Kasey Rivas

4

1 reference

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3 March 2020

Rama Subba Rao Vidadala

5

1 reference

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3 March 2020

Suzanne Scheele

6

1 reference

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3 March 2020

Amy E DeRocher

7

1 reference

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3 March 2020

Ryan Choi

8

1 reference

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3 March 2020

Matthew A Hulverson

9

1 reference

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3 March 2020

Lynn K Barrett

10

1 reference

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3 March 2020

Igor Bruzual

11

1 reference

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3 March 2020

Latha Kallur Siddaramaiah

12

1 reference

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3 March 2020

Keshia M Kerchner

13

1 reference

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3 March 2020

Matthew D Kurnick

14

1 reference

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3 March 2020

Gail M Freiberg

15

1 reference

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3 March 2020

Dale Kempf

16

1 reference

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3 March 2020

Ethan A Merritt

18

1 reference

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3 March 2020

Georg Neckermann

19

1 reference

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3 March 2020

Eugenio L de Hostos

20

1 reference

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3 March 2020

Nina Isoherranen

21

1 reference

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3 March 2020

J Stone Doggett

24

1 reference

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3 March 2020

Wesley C Van Voorhis

25

1 reference

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3 March 2020

Erkang Fan

26

1 reference

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3 March 2020

publication date

22 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693272%20AND%20SRC:MED&resulttype=core&format=json

ACS Medicinal Chemistry Letters

3 March 2020

published in

1 reference

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3 March 2020

volume

6

1 reference

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3 March 2020

issue

12

1 reference

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3 March 2020

page(s)

1184-1189

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693272%20AND%20SRC:MED&resulttype=core&format=json

Tricyclic covalent inhibitors selectively target Jak3 through an active site thiol.

3 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Potent and Selective Inhibitors of CDPK1 from T. gondii and C. parvum Based on a 5-Aminopyrazole-4-carboxamide Scaffold

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Optimizing small molecule inhibitors of calcium-dependent protein kinase 1 to prevent infection by Toxoplasma gondii

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Discovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondii

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Structures of apicomplexan calcium-dependent protein kinases reveal mechanism of activation by calcium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Use of the kinase inhibitor analog 1NM-PP1 reveals a role for Toxoplasma gondii CDPK1 in the invasion step

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Calcium-dependent signaling and kinases in apicomplexan parasites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Apical organelle discharge by Cryptosporidium parvum is temperature, cytoskeleton, and intracellular calcium dependent and required for host cell invasion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Kinetics of parasite burdens in blood and tissues during murine toxoplasmosis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Development and applications of a broad-coverage, TR-FRET-based kinase binding assay platform.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

A second-site suppressor strategy for chemical genetic analysis of diverse protein kinases.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Intracellular calcium stores in Toxoplasma gondii govern invasion of host cells

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4677665

Attachment of Toxoplasma gondii to host cells involves major surface protein, SAG-1 (P30)

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26693272

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ACSMEDCHEMLETT.5B00319

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693272%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693272%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26693272%20AND%20SRC:MED&resulttype=core&format=json