(Q51758312)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

author

Christopher R Martens

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

author name string

Blair A Denman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Melissa R Mazzo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Michael L Armstrong

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Nichole Reisdorph

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Matthew B McQueen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Michel Chonchol

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Douglas R Seals

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

language of work or name

English

0 references

publication date

29 March 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

published in

Nature Communications

1 reference

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21 March 2020

volume

9

1 reference

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21 March 2020

issue

1

1 reference

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21 March 2020

page(s)

1286

1 reference

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Creative Commons Attribution 4.0 International

21 March 2020

copyright license

start time

29 March 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

1 reference

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Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

22 June 2018

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Practical alternatives to chronic caloric restriction for optimizing vascular function with ageing.

22 June 2018

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Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle

22 June 2018

1 reference

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Aortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia

22 June 2018

1 reference

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Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice

22 June 2018

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Oral trehalose supplementation improves resistance artery endothelial function in healthy middle-aged and older adults

22 June 2018

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Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice.

22 June 2018

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Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association

22 June 2018

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Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: a pilot trial in middle-aged and older adults

22 June 2018

1 reference

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Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults

22 June 2018

1 reference

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A Randomized Trial of Intensive versus Standard Blood-Pressure Control

22 June 2018

1 reference

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Reducing the Blood Pressure-Related Burden of Cardiovascular Disease: Impact of Achievable Improvements in Blood Pressure Prevention and Control

22 June 2018

1 reference

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Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-Obese Younger Adults: A Randomized Clinical Trial

22 June 2018

1 reference

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In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences

22 June 2018

1 reference

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Mechanism of inhibition of the human sirtuin enzyme SIRT3 by nicotinamide: computational and experimental studies

22 June 2018

1 reference

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Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: possible role of nuclear factor κB.

22 June 2018

1 reference

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Arterial stiffness and hypertension: chicken or egg?

22 June 2018

1 reference

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Targeted, LCMS-based Metabolomics for Quantitative Measurement of NAD(+) Metabolites

22 June 2018

1 reference

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Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging

22 June 2018

1 reference

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Vascular endothelial function and oxidative stress are related to dietary niacin intake among healthy middle-aged and older adults

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Nicotinamide riboside, a trace nutrient in foods, is a vitamin B3 with effects on energy metabolism and neuroprotection

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

NAD⁺ metabolism: a therapeutic target for age-related metabolic disease

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Motor assessment using the NIH Toolbox

22 June 2018

1 reference

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Recent advances in calorie restriction research on aging.

22 June 2018

1 reference

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Dietary sodium restriction reverses vascular endothelial dysfunction in middle-aged/older adults with moderately elevated systolic blood pressure

22 June 2018

1 reference

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Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging

22 June 2018

1 reference

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Aortic stiffness, blood pressure progression, and incident hypertension

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Tetrahydrobiopterin supplementation enhances carotid artery compliance in healthy older men: a pilot study

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Niacin: chemical forms, bioavailability, and health effects

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Pulse wave velocity is associated with muscle mass decline: Health ABC study

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Arterial stiffness in chronic kidney disease: causes and consequences

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Arterial destiffening with weight loss in overweight and obese middle-aged and older adults

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Adherence to healthy lifestyle habits in US adults, 1988-2006.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Stopping to rest during a 400-meter walk and incident mobility disability in older persons with functional limitations

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

The danger of weight loss in the elderly

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Tissue-specific regulation of SIRT1 by calorie restriction

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Weight loss alone improves conduit and resistance artery endothelial function in young and older overweight/obese adults

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Expert consensus document on arterial stiffness: methodological issues and clinical applications

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Calorie restriction mimetics: an emerging research field

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Aortic stiffness is an independent predictor of progression to hypertension in nonhypertensive subjects

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure<SUBTITLE>The JNC 7 Report</SUBTITLE>

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

The Standing Heel-Rise Test for Ankle Plantar Flexion: Criterion for Normal

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

One-sided or two-sided ρ values: which most appropriately address the question of drug efficacy?

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Caloric restriction lowers blood pressure in the spontaneously hypertensive rat.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Prehypertension is real and can be associated with target organ damage

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Circadian Reprogramming in the Liver Identifies Metabolic Pathways of Aging

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Activation of SIRT1 Attenuates Klotho Deficiency-Induced Arterial Stiffness and Hypertension by Enhancing AMP-Activated Protein Kinase Activity

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Arterial stiffness is associated with low thigh muscle mass in middle-aged to elderly men.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Thermogenic responsiveness to beta-adrenergic stimulation is augmented in exercising versus sedentary adults: role of oxidative stress

13 August 2018

1 reference

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Characterization of determinants of ligand binding to the nicotinic acid receptor GPR109A (HM74A/PUMA-G).

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Ascorbic acid selectively improves large elastic artery compliance in postmenopausal women

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Ascorbic acid does not affect large elastic artery compliance or central blood pressure in young and older men.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

Oxidative stress does not modulate metabolic rate or skeletal muscle sympathetic activity with primary aging in adult humans

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5876407

SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans

13 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-03421-7

7 January 2021

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Executive Summary: A Report of the American College of Cardiology/American Heart Association

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-03421-7

7 January 2021

Arterial stiffness and hormone replacement use in healthy postmenopausal women

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-03421-7

7 January 2021

Absence of age-related increase in central arterial stiffness in physically active women

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-03421-7

7 January 2021

Regular exercise, hormone replacement therapy and the age-related decline in carotid arterial compliance in healthy women

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-03421-7

7 January 2021

Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-03421-7

7 January 2021

Tests of stepping as indicators of mobility, balance, and fall risk in balance-impaired older adults

1 reference

https://api.crossref.org/works/10.1038%2FS41467-018-03421-7

7 January 2021

Relationship of knee extension force to independence in sit-to-stand performance in patients receiving acute rehabilitation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29599478

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41467-018-03421-7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29599478%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

29599478

1 reference