(Q51773605)

12 April 2018

title

Tumour-associated glycan modifications of antigen enhance MGL2 dependent uptake and MHC class I restricted CD8 T cell responses. (English)

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12 April 2018

6

Yvette van Kooyk

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12 April 2018

author name string

Satwinder Kaur Singh

1

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12 April 2018

Ingeborg Streng-Ouwehand

2

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12 April 2018

Manja Litjens

3

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12 April 2018

Hakan Kalay

4

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12 April 2018

Eirikur Saeland

5

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12 April 2018

language of work or name

English

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publication date

1 March 2011

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12 April 2018

International Journal of Cancer

published in

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12 April 2018

volume

128

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12 April 2018

page(s)

1371-1383

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12 April 2018

issue

6

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12 April 2018

Toll-like receptors and microbes take aim at each other

cites work

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The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

21 January 2018

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Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

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The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

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The mannose receptor mediates uptake of soluble but not of cell-associated antigen for cross-presentation

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Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

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Antigen presentation to CD8+ T cells: cross-priming in infectious diseases.

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Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens

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ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells

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Phagosomes are competent organelles for antigen cross-presentation

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Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo

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Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

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Differential antigen processing by dendritic cell subsets in vivo

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Expression of human DEC-205 (CD205) multilectin receptor on leukocytes.

21 January 2018

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The macrophage C-type lectin specific for galactose/N-acetylgalactosamine is an endocytic receptor expressed on monocyte-derived immature dendritic cells

21 January 2018

1 reference

Molecular cloning and characterization of a novel mouse macrophage C-type lectin, mMGL2, which has a distinct carbohydrate specificity from mMGL1

21 January 2018

1 reference

Characterization of murine MGL1 and MGL2 C-type lectins: distinct glycan specificities and tumor binding properties

21 January 2018

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Carbohydrate profiling reveals a distinctive role for the C-type lectin MGL in the recognition of helminth parasites and tumor antigens by dendritic cells

21 January 2018

1 reference

The amino acids involved in the distinct carbohydrate specificities between macrophage galactose-type C-type lectins 1 and 2 (CD301a and b) of mice

21 January 2018

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Macrophage C-type lectin on bone marrow-derived immature dendritic cells is involved in the internalization of glycosylated antigens

21 January 2018

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Generation of mice deficient for macrophage galactose- and N-acetylgalactosamine-specific lectin: limited role in lymphoid and erythroid homeostasis and evidence for multiple lectins

21 January 2018

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The dermal microenvironment induces the expression of the alternative activation marker CD301/mMGL in mononuclear phagocytes, independent of IL-4/IL-13 signaling.

21 January 2018

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Interaction of human macrophage C-type lectin with O-linked N-acetylgalactosamine residues on mucin glycopeptides

21 January 2018

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The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma.

21 January 2018

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Cancer biomarkers defined by autoantibody signatures to aberrant O-glycopeptide epitopes

21 January 2018

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Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells

21 January 2018

1 reference

Comparison of the carbohydrate-binding specificities of seven N-acetyl-D-galactosamine-recognizing lectins

21 January 2018

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Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

21 January 2018

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MGL-mediated internalization and antigen presentation by dendritic cells: a role for tyrosine-5.

21 January 2018

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MGL2 Dermal dendritic cells are sufficient to initiate contact hypersensitivity in vivo

21 January 2018

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A model vaccine exploiting fungal mannosylation to increase antigen immunogenicity

21 January 2018

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Complex carbohydrates are not removed during processing of glycoproteins by dendritic cells: processing of tumor antigen MUC1 glycopeptides for presentation to major histocompatibility complex class II-restricted T cells

21 January 2018

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O-Linked glycans control glycoprotein processing by antigen-presenting cells: a biochemical approach to the molecular aspects of MUC1 processing by dendritic cells

21 January 2018

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MUC1 and the immunobiology of cancer

21 January 2018

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Presentation of MUC1 tumor antigen by class I MHC and CTL function correlate with the glycosylation state of the protein taken Up by dendritic cells

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O-glycosylated versus non-glycosylated MUC1-derived peptides as potential targets for cytotoxic immunotherapy of carcinoma.

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Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

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21 January 2018

Identifiers

DOI

10.1002/IJC.25458

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12 April 2018

PubMed ID

20473945

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12 April 2018