(Q51786825)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Analysis of wntless (WLS) expression in gastric, ovarian, and breast cancers reveals a strong association with HER2 overexpression (English)

1 reference

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20 February 2020

1 reference

15

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20 February 2020

Kenneth Arthur

5

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20 February 2020

Darragh G. McArt

8

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20 February 2020

Jia Yu

14

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author name string

Jonathan Stewart

1

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20 February 2020

Jacqueline James

2

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20 February 2020

Glenn W McCluggage

3

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20 February 2020

Stephen McQuaid

4

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20 February 2020

David Boyle

6

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20 February 2020

Paul Mullan

7

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20 February 2020

Benedict Yan

9

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20 February 2020

Gareth Irwin

10

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20 February 2020

D Paul Harkin

11

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20 February 2020

Lei Zhengdeng

12

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20 February 2020

Chee-Wee Ong

13

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20 February 2020

Manuel Salto-Tellez

16

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20 February 2020

publication date

26 September 2014

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20 February 2020

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20 February 2020

volume

28

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20 February 2020

issue

3

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20 February 2020

page(s)

428-436

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Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells

20 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Secretion of Wnt ligands requires Evi, a conserved transmembrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities

21 January 2018

1 reference

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The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Wnt-signalling pathway in ovarian epithelial tumours: increased expression of beta-catenin and GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Mutations in components of the Wnt signaling pathway in gastric cancer

21 January 2018

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Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression

21 January 2018

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A study of HER2 gene amplification and protein expression in gastric cancer

21 January 2018

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Sequential expression of putative stem cell markers in gastric carcinogenesis

21 January 2018

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TRARESA: a tissue microarray-based hospital system for biomarker validation and discovery.

21 January 2018

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Tissue microarrays characterise the clinical significance of a VEGF-A protein expression signature in gastrointestinal stromal tumours

21 January 2018

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Epithelial-mesenchymal transition in malignant mesothelioma

21 January 2018

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Activation of sonic hedgehog signaling in oral squamous cell carcinomas: a preliminary study

21 January 2018

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Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features

21 January 2018

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Wnt signaling in ovarian tumorigenesis

21 January 2018

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Wnt signaling and breast cancer

21 January 2018

1 reference

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Loss of beta-catenin expression in metastatic gastric cancer

21 January 2018

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Mutations and nuclear accumulation of beta-catenin correlate with intestinal phenotypic expression in human gastric cancer.

21 January 2018

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HER2 as a Prognostic Marker in Gastric Cancer - A Systematic Analysis of Data from the Literature

21 January 2018

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Overexpression of ErbB2 in cancer and ErbB2-targeting strategies

21 January 2018

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Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

21 January 2018

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A phase I study of lapatinib in combination with carboplatin in women with platinum sensitive recurrent ovarian carcinoma.

21 January 2018

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Phase II trial of lapatinib and topotecan (LapTop) in patients with platinum-refractory/resistant ovarian and primary peritoneal carcinoma

21 January 2018

1 reference

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Clinical activity of gemcitabine plus pertuzumab in platinum-resistant ovarian cancer, fallopian tube cancer, or primary peritoneal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Cytoplasmic localization of beta-catenin is a marker of poor outcome in breast cancer patients.

21 January 2018

1 reference

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Targeting androgen receptor in estrogen receptor-negative breast cancer

21 January 2018

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β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation

21 January 2018

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Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse

21 January 2018

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Genomics of the NF-κB signaling pathway: hypothesized role in ovarian cancer

21 January 2018

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Wnt signaling requires retromer-dependent recycling of MIG-14/Wntless in Wnt-producing cells

21 January 2018

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The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer

21 January 2018

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Inducible nuclear factor-kappaB activation contributes to chemotherapy resistance in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis

21 January 2018

1 reference

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Targeting breast cancer stem cells

21 January 2018

1 reference

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Targeting Wnt pathways in disease

21 January 2018

1 reference

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Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

21 January 2018

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21 January 2018

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Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status

21 January 2018

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Overexpression of c-erbB-2 protein in gastric cancer. Its correlation with long-term survival of patients

21 January 2018

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12 December 2020

Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts

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12 December 2020

Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer

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12 December 2020

HER-2 and NF-kappaB as the targets for therapy-resistant breast cancer

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12 December 2020

Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer

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12 December 2020

HER-2/neu oncogene protein and prognosis in breast cancer

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12 December 2020

beta-catenin mutation and expression analysis in ovarian cancer: exon 3 mutations and nuclear translocation in 16% of endometrioid tumours

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12 December 2020

The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas

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12 December 2020

Involvement of adenomatous polyposis coli (APC)/beta-catenin signalling in human breast cancer

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12 December 2020

APC truncation and increased beta-catenin levels in a human breast cancer cell line

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12 December 2020

Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology Group

1 reference

12 December 2020

Canonical and noncanonical Wnt pathway: a comparison among normal ovary, benign ovarian tumor and ovarian cancer

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12 December 2020

Relationship of C-erbB-2 protein expression and gene amplification to invasion and metastasis in human gastric cancer

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12 December 2020

Taxane resistance in breast cancer: a closed HER2 circuit?

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12 December 2020

HER2: biology, detection, and clinical implications

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12 December 2020

10.1038/MODPATHOL.2014.114

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference