(Q51786825)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Analysis of wntless (WLS) expression in gastric, ovarian, and breast cancers reveals a strong association with HER2 overexpression (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Kenneth Arthur

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Darragh G. McArt

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Jia Yu

14

0 references

author name string

Jonathan Stewart

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Jacqueline James

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Glenn W McCluggage

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Stephen McQuaid

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

David Boyle

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Paul Mullan

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Benedict Yan

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Gareth Irwin

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

D Paul Harkin

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Lei Zhengdeng

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Chee-Wee Ong

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Manuel Salto-Tellez

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

publication date

26 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

page(s)

428-436

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/modpathol.2014.114

20 February 2020

exact match

0 references

cites work

Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Secretion of Wnt ligands requires Evi, a conserved transmembrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Wnt-signalling pathway in ovarian epithelial tumours: increased expression of beta-catenin and GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Increased beta-catenin mRNA levels and mutational alterations of the APC and beta-catenin gene are present in intestinal-type gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Mutations in components of the Wnt signaling pathway in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

A study of HER2 gene amplification and protein expression in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Sequential expression of putative stem cell markers in gastric carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

TRARESA: a tissue microarray-based hospital system for biomarker validation and discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Tissue microarrays characterise the clinical significance of a VEGF-A protein expression signature in gastrointestinal stromal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Epithelial-mesenchymal transition in malignant mesothelioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Activation of sonic hedgehog signaling in oral squamous cell carcinomas: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Wnt signaling in ovarian tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Wnt signaling and breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Loss of beta-catenin expression in metastatic gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Mutations and nuclear accumulation of beta-catenin correlate with intestinal phenotypic expression in human gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

HER2 as a Prognostic Marker in Gastric Cancer - A Systematic Analysis of Data from the Literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Overexpression of ErbB2 in cancer and ErbB2-targeting strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

A phase I study of lapatinib in combination with carboplatin in women with platinum sensitive recurrent ovarian carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Phase II trial of lapatinib and topotecan (LapTop) in patients with platinum-refractory/resistant ovarian and primary peritoneal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Clinical activity of gemcitabine plus pertuzumab in platinum-resistant ovarian cancer, fallopian tube cancer, or primary peritoneal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Cytoplasmic localization of beta-catenin is a marker of poor outcome in breast cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Targeting androgen receptor in estrogen receptor-negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Genomics of the NF-κB signaling pathway: hypothesized role in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Wnt signaling requires retromer-dependent recycling of MIG-14/Wntless in Wnt-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Inducible nuclear factor-kappaB activation contributes to chemotherapy resistance in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Targeting breast cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Targeting Wnt pathways in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Phase II study of efficacy, safety, and pharmacokinetics of trastuzumab monotherapy administered on a 3-weekly schedule.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Clinical activity of pertuzumab (rhuMAb 2C4), a HER dimerization inhibitor, in advanced ovarian cancer: potential predictive relationship with tumor HER2 activation status

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.2014.114

Overexpression of c-erbB-2 protein in gastric cancer. Its correlation with long-term survival of patients

21 January 2018

1 reference

12 December 2020

Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts

1 reference

12 December 2020

Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer

1 reference

12 December 2020

HER-2 and NF-kappaB as the targets for therapy-resistant breast cancer

1 reference

12 December 2020

Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer

1 reference

12 December 2020

HER-2/neu oncogene protein and prognosis in breast cancer

1 reference

12 December 2020

beta-catenin mutation and expression analysis in ovarian cancer: exon 3 mutations and nuclear translocation in 16% of endometrioid tumours

1 reference

12 December 2020

The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas

1 reference

12 December 2020

Involvement of adenomatous polyposis coli (APC)/beta-catenin signalling in human breast cancer

1 reference

12 December 2020

APC truncation and increased beta-catenin levels in a human breast cancer cell line

1 reference

12 December 2020

Evaluation of monoclonal humanized anti-HER2 antibody, trastuzumab, in patients with recurrent or refractory ovarian or primary peritoneal carcinoma with overexpression of HER2: a phase II trial of the Gynecologic Oncology Group

1 reference

12 December 2020

Canonical and noncanonical Wnt pathway: a comparison among normal ovary, benign ovarian tumor and ovarian cancer

1 reference

12 December 2020

Relationship of C-erbB-2 protein expression and gene amplification to invasion and metastasis in human gastric cancer

1 reference

12 December 2020

Taxane resistance in breast cancer: a closed HER2 circuit?

1 reference

12 December 2020

HER2: biology, detection, and clinical implications

1 reference

12 December 2020

10.1038/MODPATHOL.2014.114

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25258105%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference