(Q51790921)

12 April 2018

title

Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase. (English)

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author

Carlos Olano

1

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author name string

Barrie Wilkinson

2

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Steven J Moss

3

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Alfredo F Braña

4

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Carmen Méndez

5

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Peter F Leadlay

6

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José A Salas

7

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language of work or name

English

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publication date

1 November 2003

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12 April 2018

published in

Chemical Communications

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issue

22

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page(s)

2780-2782

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Genetic Contributions to Understanding Polyketide Synthases

cites work

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Metabolic engineering--a genetic toolbox for small molecule organic synthesis

21 January 2018

1 reference

Combinatorial biosynthesis of polyketides and nonribosomal peptides

21 January 2018

1 reference

Natural product biosynthesis: a new interface between enzymology and medicine

21 January 2018

1 reference

Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules

21 January 2018

1 reference

Role of linkers in communication between protein modules

21 January 2018

1 reference

A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity

21 January 2018

1 reference

The hidden steps of domain skipping: macrolactone ring size determination in the pikromycin modular polyketide synthase

21 January 2018

1 reference

The biosynthesis of the aromatic myxobacterial electron transport inhibitor stigmatellin is directed by a novel type of modular polyketide synthase

21 January 2018

1 reference

The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.

21 January 2018

1 reference

New natural epothilones from Sorangium cellulosum, strains So ce90/B2 and So ce90/D13: isolation, structure elucidation, and SAR studies

21 January 2018

1 reference

First in vitro directed biosynthesis of new compounds by a minimal type II polyketide synthase: evidence for the mechanism of chain length determination.

21 January 2018

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The crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Synechocystis sp. at 1.54 A resolution and its relationship to other condensing enzymes

21 January 2018

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Alternative modular polyketide synthase expression controls macrolactone structure

21 January 2018

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Biochemical and Immunological Characterization of Threonyl-tRNA Synthetase of Two Borrelidin-Resistant Mutants of Escherichia coli K12

21 January 2018

1 reference

Borrelidin is an angiogenesis inhibitor; disruption of angiogenic capillary vessels in a rat aorta matrix culture model.

21 January 2018

1 reference

Borrelidin inhibits a cyclin-dependent kinase (CDK), Cdc28/Cln2, of Saccharomyces cerevisiae

21 January 2018

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Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1039/B310648A

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12 April 2018