(Q51803381)

12 April 2018

title

Rac is a dominant regulator of cadherin-directed actin assembly that is activated by adhesive ligation independently of Tiam1. (English)

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12 April 2018

author

Alpha Yap

4

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12 April 2018

author name string

Astrid Kraemer

1

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12 April 2018

Marita Goodwin

2

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12 April 2018

Suzie Verma

3

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12 April 2018

Radiya G Ali

5

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12 April 2018

publication date

4 October 2006

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12 April 2018

American Journal of Physiology - Cell Physiology

published in

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12 April 2018

volume

292

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12 April 2018

page(s)

C1061-9

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12 April 2018

issue

3

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12 April 2018

Mechanism for transition from initial to stable cell-cell adhesion: kinetic analysis of E-cadherin-mediated adhesion using a quantitative adhesion assay

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Tiam1-IRSp53 complex formation directs specificity of rac-mediated actin cytoskeleton regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Minimal mutation of the cytoplasmic tail inhibits the ability of E-cadherin to activate Rac but not phosphatidylinositol 3-kinase: direct evidence of a role for cadherin-activated Rac signaling in adhesion and contact formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Cortactin is necessary for E-cadherin-mediated contact formation and actin reorganization

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

E-cadherin homophilic ligation directly signals through Rac and phosphatidylinositol 3-kinase to regulate adhesive contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Cadherin-directed actin assembly: E-cadherin physically associates with the Arp2/3 complex to direct actin assembly in nascent adhesive contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Signaling to actin dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

The Rac exchange factor Tiam1 is required for the establishment and maintenance of cadherin-based adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Roles of STEF/Tiam1, guanine nucleotide exchange factors for Rac1, in regulation of growth cone morphology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Cadherin engagement regulates Rho family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Activation of Rac and Cdc42 by integrins mediates cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Ena/VASP proteins can regulate distinct modes of actin organization at cadherin-adhesive contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Morphogenetic roles of classic cadherins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Cadherins in embryonic and neural morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Directed actin polymerization is the driving force for epithelial cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Arp2/3 activity is necessary for efficient formation of E-cadherin adhesive contacts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

Direct cadherin-activated cell signaling: a view from the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPCELL.00073.2006

10.1152/AJPCELL.00073.2006

21 January 2018

Identifiers

DOI

1 reference

12 April 2018

PubMed ID

17020937

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12 April 2018