(Q51806436)

12 April 2018

title

Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding. (English)

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12 April 2018

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8

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12 April 2018

Mohammad Al-Tamimi

object named as

Mohammad Al-Tamimi

1

0 references

Robert K. Andrews

object named as

Robert K Andrews

7

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author name string

Fi-Tjen Mu

2

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12 April 2018

Jane F Arthur

3

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12 April 2018

Yang Shen

4

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12 April 2018

Masaaki Moroi

5

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12 April 2018

Michael C Berndt

6

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12 April 2018

publication date

1 March 2009

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12 April 2018

published in

Platelets

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12 April 2018

volume

20

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12 April 2018

issue

2

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12 April 2018

page(s)

75-82

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12 April 2018

Platelet-collagen interaction: is GPVI the central receptor?

cites work

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcalphaR and the natural killer receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Programmed autologous cleavage of platelet receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Controlled shedding of platelet glycoprotein (GP)VI and GPIb-IX-V by ADAM family metalloproteinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Dual ITAM-mediated proteolytic pathways for irreversible inactivation of platelet receptors: de-ITAM-izing FcgammaRIIa

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Compromised ITAM-based platelet receptor function in a patient with immune thrombocytopenic purpura.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Diverging signaling events control the pathway of GPVI down-regulation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

The Fab fragment of a novel anti-GPVI monoclonal antibody, OM4, reduces in vivo thrombosis without bleeding risk in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

A novel antiplatelet antibody therapy that induces cAMP-dependent endocytosis of the GPVI/Fc receptor gamma-chain complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti-human platelet agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Identification of residues within human glycoprotein VI involved in the binding to collagen: evidence for the existence of distinct binding sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Integrin alpha 2 beta 1-independent activation of platelets by simple collagen-like peptides: collagen tertiary (triple-helical) and quaternary (polymeric) structures are sufficient alone for alpha 2 beta 1-independent platelet reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

The cytoplasmic domain of the platelet glycoprotein Ibalpha is phosphorylated at serine 609.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Identification of a second class of IgG Fc receptors on human neutrophils. A 40 kilodalton molecule also found on eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Anti-GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

Platelet glycoprotein VI: a novel marker for acute coronary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09537100802645029

10.1080/09537100802645029

21 January 2018

Identifiers

DOI

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12 April 2018

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12 April 2018