(Q51809142)

12 April 2018

editorial

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title

Chimeric T cells for adoptive immunotherapy of cancer: using what have we learned to plan for the future. (English)

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12 April 2018

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2

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author name string

Stefan Peinert

series ordinal

1

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12 April 2018

H Miles Prince

series ordinal

3

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publication date

1 November 2009

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12 April 2018

published in

Immunotherapy

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12 April 2018

volume

1

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issue

6

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12 April 2018

page(s)

905-912

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A fresh look at tumor immunosurveillance and immunotherapy.

cites work

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Relationship of causative factors in spontaneous regression of cancer to immunologic factors possibly effective in cancer

21 January 2018

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Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

21 January 2018

1 reference

Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

21 January 2018

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Cancer regression in patients after transfer of genetically engineered lymphocytes

21 January 2018

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Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapy

21 January 2018

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Natural selection of tumor variants in the generation of "tumor escape" phenotypes

21 January 2018

1 reference

Targeting the Wilms tumor antigen 1 by TCR gene transfer: TCR variants improve tetramer binding but not the function of gene modified human T cells.

21 January 2018

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Redirecting mouse CTL against colon carcinoma: superior signaling efficacy of single-chain variable domain chimeras containing TCR-zeta vs Fc epsilon RI-gamma

21 January 2018

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Reversal in the immunodominance hierarchy in secondary CD8+ T cell responses to influenza A virus: roles for cross-presentation and lysis-independent immunodomination

21 January 2018

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Transition of late-stage effector T cells to CD27+ CD28+ tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy

21 January 2018

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CD28-mediated co-stimulation: a quantitative support for TCR signalling

21 January 2018

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Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production

21 January 2018

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Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain

21 January 2018

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Supernatural T cells: genetic modification of T cells for cancer therapy

21 January 2018

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Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15.

21 January 2018

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Adoptive transfer of T cells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice

21 January 2018

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T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells

21 January 2018

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Targeted elimination of prostate cancer by genetically directed human T lymphocytes

21 January 2018

1 reference

Gene-engineered T cells as a superior adjuvant therapy for metastatic cancer

21 January 2018

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A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer

21 January 2018

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Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

21 January 2018

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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

21 January 2018

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Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals

21 January 2018

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

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Resistance of mature T cells to oncogene transformation

21 January 2018

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Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer

21 January 2018

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Retroviral gene transfer using safe and efficient packaging cell lines

21 January 2018

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Clinical scale production of an improved retroviral vector expressing the human multidrug resistance 1 gene (MDR1).

21 January 2018

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Absence of retroviral vector-mediated transformation of gene-modified T cells after long-term engraftment in mice

21 January 2018

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A phase II randomized study of HIV-specific T-cell gene therapy in subjects with undetectable plasma viremia on combination antiretroviral therapy

21 January 2018

1 reference

Escape from immunotherapy: possible mechanisms that influence tumor regression/progression.

21 January 2018

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CD8+ T-cell memory in tumor immunology and immunotherapy

21 January 2018

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Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

21 January 2018

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IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes

21 January 2018

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IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

21 January 2018

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Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling.

21 January 2018

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Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy.

21 January 2018

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Rejection of Syngeneic Colon Carcinoma by CTLs Expressing Single-Chain Antibody Receptors Codelivering CD28 Costimulation

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/IMT.09.69

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12 April 2018

PubMed ID

20635906

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12 April 2018