(Q51816156)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Characterization of intestinal and hepatic P450 enzymes in cynomolgus monkeys with typical substrates and inhibitors for human P450 enzymes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Noriaki Yoda

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Shoichi Date

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Satoshi Kondo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Masateru Miyake

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Satoru Nakazato

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Ken Umehara

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Eiji Kashiyama

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

1 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

719-730

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22324396%20AND%20SRC:MED&resulttype=core&format=json

Validation of (-)-N-3-benzyl-phenobarbital as a selective inhibitor of CYP2C19 in human liver microsomes

22 January 2020

cites work

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

In vitro inhibitory effect of 1-aminobenzotriazole on drug oxidations in human liver microsomes: a comparison with SKF-525A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Cynomolgus monkey CYPs: a comparison with human CYPs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Comparison of cytochrome P450 3A enzymes in cynomolgus monkeys and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Species difference in nisoldipine oxidation activity in the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Extrapolation of diclofenac clearance from in vitro microsomal metabolism data: role of acyl glucuronidation and sequential oxidative metabolism of the acyl glucuronide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

In vitro assessment of cytochrome P450 inhibition: strategies for increasing LC/MS-based assay throughput using a one-point IC(50) method and multiplexing high-performance liquid chromatography.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Molecular cloning, expression, and characterization of CYP2D17 from cynomolgus monkey liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Tissue-specific mRNA expression profiles of drug-metabolizing enzymes and transporters in the cynomolgus monkey.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Effect of oral ketoconazole on intestinal first-pass effect of midazolam and fexofenadine in cynomolgus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

First-pass metabolism of midazolam by the human intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

The human intestinal cytochrome P450 "pie".

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Summary of information on human CYP enzymes: human P450 metabolism data

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Marked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Immunochemical detection of cytochrome P450 enzymes in liver microsomes of 27 cynomolgus monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

CYP2C76, a novel cytochrome P450 in cynomolgus monkey, is a major CYP2C in liver, metabolizing tolbutamide and testosterone

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function.

21 January 2018

1 reference

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Validated assays for human cytochrome P450 activities

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Drug metabolism and variability among patients in drug response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Species Difference between Cynomolgus Monkeys and Humans on Cytochromes P450 2D and 3A-Dependent Drug Oxidation Activities in Liver Microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732

Metabolism of P450 Probe Substrates by Cynomolgus Monkey CYP2C76

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.656732