(Q51932954)

17 April 2018

title

Modeling the structure of the StART domains of MLN64 and StAR proteins in complex with cholesterol. (English)

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17 April 2018

main subject

protein structure

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author

Frederick R. Maxfield

3

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17 April 2018

author name string

Marta Murcia

1

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17 April 2018

José D Faráldo-Gómez

2

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17 April 2018

Benoît Roux

4

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17 April 2018

publication date

21 September 2006

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17 April 2018

Journal of Lipid Research

published in

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17 April 2018

volume

47

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17 April 2018

issue

12

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17 April 2018

page(s)

2614-2630

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17 April 2018

Neurosteroids: the StAR protein in the brain.

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21 January 2018

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Structure of a conserved hypothetical protein, TTHA0849 from Thermus thermophilus HB8, at 2.4 A resolution: a putative member of the StAR-related lipid-transfer (START) domain superfamily.

21 January 2018

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Incorrect folding of steroidogenic acute regulatory protein (StAR) in congenital lipoid adrenal hyperplasia

21 January 2018

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CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

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Improved treatment of the protein backbone in empirical force fields.

21 January 2018

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21 January 2018

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21 January 2018

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Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

21 January 2018

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Virtual screening with flexible docking and COMBINE-based models. Application to a series of factor Xa inhibitors

21 January 2018

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21 January 2018

Implicit solvent models

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 January 2018

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A graph-theory algorithm for rapid protein side-chain prediction

21 January 2018

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Calculation of absolute protein-ligand binding free energy from computer simulations

21 January 2018

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Calculation of cyclodextrin binding affinities: energy, entropy, and implications for drug design

21 January 2018

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On the calculation of absolute macromolecular binding free energies

21 January 2018

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Recent advances in the development and application of implicit solvent models in biomolecule simulations

21 January 2018

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Assessing scoring functions for protein-ligand interactions

21 January 2018

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The steroidogenic acute regulatory protein, StAR, works only at the outer mitochondrial membrane

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cholesterol interactions with phospholipids in membranes

21 January 2018

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Anisotropic motion of cholesterol in oriented DPPC bilayers studied by quasielastic neutron scattering: the liquid-ordered phase

21 January 2018

1 reference

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Human StarD5, a cytosolic StAR-related lipid binding protein

21 January 2018

1 reference

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The 1.45 A resolution structure of the cryptogein-cholesterol complex: a close-up view of a sterol carrier protein (SCP) active site

21 January 2018

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Structural mechanism for sterol sensing and transport by OSBP-related proteins

21 January 2018

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A computational procedure for determining energetically favorable binding sites on biologically important macromolecules

21 January 2018

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21 January 2018

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Simple, Intuitive Calculations of Free Energy of Binding for Protein−Ligand Complexes. 3. The Free Energy Contribution of Structural Water Molecules in HIV-1 Protease Complexes

21 January 2018

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Insights into steroidogenic acute regulatory protein (StAR)-dependent cholesterol transfer in mitochondria: evidence from molecular modeling and structure-based thermodynamics supporting the existence of partially unfolded states of StAR.

21 January 2018

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Phosphorylation and function of the hamster adrenal steroidogenic acute regulatory protein (StAR).

21 January 2018

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Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A

21 January 2018

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The active form of the steroidogenic acute regulatory protein, StAR, appears to be a molten globule

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600232-JLR200

A pH-dependent molten globule transition is required for activity of the steroidogenic acute regulatory protein, StAR.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M600232-JLR200

Evidence that StAR and MLN64 act on the outer mitochondrial membrane as molten globules

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600232-JLR200

N-218 MLN64, a protein with StAR-like steroidogenic activity, is folded and cleaved similarly to StAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600232-JLR200

Binding of steroidogenic acute regulatory protein to synthetic membranes suggests an active molten globule

21 January 2018

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Molecular modeling and structure-based thermodynamic analysis of the StAR protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600232-JLR200

The structure of phosphatidylinositol transfer protein alpha reveals sites for phospholipid binding and membrane association with major implications for its function

21 January 2018

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Low energy pathways and non-native interactions: the influence of artificial disulfide bridges on the mechanism of folding

21 January 2018

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Human SOD1 before harboring the catalytic metal: solution structure of copper-depleted, disulfide-reduced form

21 January 2018

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Crystal structure of Escherichia coli thiol peroxidase in the oxidized state: insights into intramolecular disulfide formation and substrate binding in atypical 2-Cys peroxiredoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600232-JLR200

MLN64 contains a domain with homology to the steroidogenic acute regulatory protein (StAR) that stimulates steroidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600232-JLR200

Biological functions of phosphatidylinositol transfer proteins

21 January 2018

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Structure of PITPbeta in complex with phosphatidylcholine: comparison of structure and lipid transfer to other PITP isoforms

21 January 2018

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Structure of a cholesterol-binding protein deficient in Niemann-Pick type C2 disease

21 January 2018

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The structural determination of an insect sterol carrier protein-2 with a ligand-bound C16 fatty acid at 1.35-A resolution

21 January 2018

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Nonspecific lipid-transfer proteins in plant foods and pollens: an important allergen class

21 January 2018

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Identification of non-specific lipid transfer protein-1 as a calmodulin-binding protein in Arabidopsis

21 January 2018

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Binding mechanism of nonspecific lipid transfer proteins and their role in plant defense

21 January 2018

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The 2.1 Å structure of an elicitin-ergosterol complex: A recent addition to the Sterol Carrier Protein family

21 January 2018

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Crystal structure of a fungal elicitor secreted by Phytophthora cryptogea, a member of a novel class of plant necrotic proteins

21 January 2018

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Structure of bovine pancreatic cholesterol esterase at 1.6 A: novel structural features involved in lipase activation

21 January 2018

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Crystal structure determination of cholesterol oxidase from Streptomyces and structural characterization of key active site mutants

21 January 2018

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Unravelling the significance of cellular fatty acid-binding proteins

21 January 2018

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VMD: visual molecular dynamics

21 January 2018

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STRIDE: a web server for secondary structure assignment from known atomic coordinates of proteins

21 January 2018

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Knowledge-based protein secondary structure assignment

21 January 2018

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10.1194/JLR.M600232-JLR200

21 January 2018

Identifiers

DOI

1 reference

17 April 2018

PubMed ID

16990645

1 reference

17 April 2018