(Q51938052)

18 April 2018

title

Overview of gene silencing by RNA interference. (English)

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18 April 2018

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Daniel H Kim

1

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18 April 2018

John J Rossi

series ordinal

2

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18 April 2018

publication date

1 March 2009

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18 April 2018

Current protocols in nucleic acid chemistry / editorial board, Serge L. Beaucage ... [et al.]

published in

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18 April 2018

volume

Chapter 16

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18 April 2018

page(s)

Unit 16.1

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18 April 2018

Approaches for chemically synthesized siRNA and vector-mediated RNAi

cites work

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https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Rational design and in vitro and in vivo delivery of Dicer substrate siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

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Progress towards in vivo use of siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Inhibition of respiratory viruses by nasally administered siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

siRNA function in RNAi: a chemical modification analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Aptamer mediated siRNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Detection of foreign RNA: implications for RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Silencing Viral Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

RNA interference is mediated by 21- and 22-nucleotide RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Therapeutic short hairpin RNA expression in the liver: viral targets and vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Modulation of HIV-1 replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Inhibiting gene expression at transcription start sites in chromosomal DNA with antigene RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Involvement of AGO1 and AGO2 in mammalian transcriptional silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Components of the DNA methylation system of chromatin control are RNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Translating the Histone Code

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Strategies for silencing human disease using RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Transvascular delivery of small interfering RNA to the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Argonaute2 is the catalytic engine of mammalian RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Nuclear export of microRNA precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

RISC is a 5' phosphomonoester-producing RNA endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Gene therapy for proliferative ocular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Lentiviral-mediated delivery of siRNAs for antiviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Small interfering RNA-induced transcriptional gene silencing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Stable suppression of gene expression by RNAi in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Prospects of RNA interference therapy for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

21 January 2018

RNAi: RISC gets loaded.

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Viral-based modelling and correction of neurodegenerative diseases by RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

MicroRNAs: expression, avoidance and subversion by vertebrate viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Antiviral innate immunity pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Noncoding RNAs and gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F0471142700.NC1601S36

10.1002/0471142700.NC1601S36

21 January 2018

Identifiers

DOI

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18 April 2018

release_lbf7lo5pqbfjpfe2zalllheprq

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lbf7lo5pqbfjpfe2zalllheprq

mapped directly with Wikidata item

24 November 2022

based on heuristic

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18 April 2018