(Q51944796)

18 April 2018

title

Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis. (English)

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18 April 2018

author

Esther Pearl

6

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18 April 2018

Laurence Bindoff

15

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18 April 2018

Siren Berland

16

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18 April 2018

Stephen Robertson

Stephen P Robertson

25

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Didier Lacombe

Didier Lacombe

12

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Valérie Cormier-Daire

Valérie Cormier-Daire

24

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Raoul Hennekam

21

Raoul C M Hennekam

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18 April 2018

author name string

Zandra A Jenkins

1

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18 April 2018

Margriet van Kogelenberg

2

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18 April 2018

Tim Morgan

3

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18 April 2018

Aaron Jeffs

4

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18 April 2018

Ryuji Fukuzawa

5

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18 April 2018

Christina Thaller

7

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18 April 2018

Anne V Hing

8

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18 April 2018

Mary E Porteous

9

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18 April 2018

Sixto Garcia-Miñaur

10

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18 April 2018

Axel Bohring

11

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18 April 2018

Fiona Stewart

13

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18 April 2018

Torunn Fiskerstrand

14

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18 April 2018

Lesley C Adès

17

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18 April 2018

Michel Tchan

18

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18 April 2018

Albert David

19

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18 April 2018

Louise C Wilson

20

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18 April 2018

Dian Donnai

22

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18 April 2018

Sahar Mansour

23

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18 April 2018

language of work or name

English

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publication date

14 December 2008

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18 April 2018

published in

Nature Genetics

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18 April 2018

volume

41

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18 April 2018

issue

1

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18 April 2018

page(s)

95-100

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18 April 2018

https://scigraph.springernature.com/pub.10.1038/ng.270

exact match

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cites work

Wnt/beta-catenin signaling in development and disease

1 reference

Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling

21 January 2018

1 reference

An X chromosome gene, WTX, is commonly inactivated in Wilms tumor

21 January 2018

1 reference

Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors

21 January 2018

1 reference

Functional inactivation of the WTX gene is not a frequent event in Wilms' tumors

21 January 2018

1 reference

A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays

21 January 2018

1 reference

Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation

21 January 2018

1 reference

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

21 January 2018

1 reference

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

21 January 2018

1 reference

High bone density due to a mutation in LDL-receptor-related protein 5

21 January 2018

1 reference

Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice

21 January 2018

1 reference

Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia.

21 January 2018

1 reference

Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia

21 January 2018

1 reference

AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane

21 January 2018

1 reference

Canonical WNT Signaling Promotes Osteogenesis by Directly StimulatingRunx2Gene Expression

21 January 2018

1 reference

High bone mass in mice expressing a mutant LRP5 gene

21 January 2018

1 reference

The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice

21 January 2018

1 reference

Essential role of beta-catenin in postnatal bone acquisition

21 January 2018

1 reference

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

21 January 2018

1 reference

Osteoblasts directly control lineage commitment of mesenchymal progenitor cells through Wnt signaling

21 January 2018

1 reference

Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

21 January 2018

1 reference

Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors.

21 January 2018

1 reference

A census of human cancer genes

21 January 2018

1 reference

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data

21 January 2018

1 reference

Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass

21 January 2018

1 reference

12 December 2020

Multiple roles of mesenchymal -catenin during murine limb patterning

1 reference

12 December 2020

Osteopathia striata-Voorhoeve's disease; report of a case presenting the features of osteopathia striata and osteopetrosis.

1 reference

12 December 2020

Tumor suppressor genes

1 reference

12 December 2020

Osteopathia striata with cranial sclerosis: literature reappraisal argues for X-linked inheritance

1 reference

12 December 2020

Identifiers

DOI

10.1038/NG.270

1 reference

18 April 2018

1 reference

18 April 2018