(Q51946101)

English

Roscovitine inhibits thyroid hormone-induced tail regression of the frog tadpole and reveals a role for cyclin C/Cdk8 in the establishment of the metamorphic gene expression program.

scientific article published in December 2008

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19035345%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Roscovitine inhibits thyroid hormone-induced tail regression of the frog tadpole and reveals a role for cyclin C/Cdk8 in the establishment of the metamorphic gene expression program (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19035345%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Caren C Helbing

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19035345%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Dominik Domański

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19035345%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

2

object named as

Nik Veldhoen

1 reference

Europe PubMed Central

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17 January 2020

author name string

Rachel C Skirrow

1

1 reference

Europe PubMed Central

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17 January 2020

publication date

1 December 2008

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Europe PubMed Central

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17 January 2020

Developmental Dynamics

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19035345%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

237

1 reference

Europe PubMed Central

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17 January 2020

12

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19035345%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

3787-3797

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19035345%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

TFIIH is negatively regulated by cdk8-containing mediator complexes

1 reference

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7 January 2021

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The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity

1 reference

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7 January 2021

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Cell-specific responses to loss of cyclin-dependent kinases.

1 reference

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7 January 2021

based on heuristic

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The thyroid hormone-induced tail resorption program during Xenopus laevis metamorphosis

1 reference

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7 January 2021

based on heuristic

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Mitogen-activated protein kinases potentiate thyroid hormone receptor transcriptional activity by stabilizing its protein

1 reference

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7 January 2021

based on heuristic

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Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase

1 reference

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7 January 2021

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Cdc2 and Cdk2 kinase activated by transforming growth factor-beta1 trigger apoptosis through the phosphorylation of retinoblastoma protein in FaO hepatoma cells

1 reference

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7 January 2021

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Potent inhibitors of cyclin-dependent kinase 2 induce nuclear accumulation of wild-type p53 and nucleolar fragmentation in human untransformed and tumor-derived cells

1 reference

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7 January 2021

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Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

1 reference

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7 January 2021

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CDK4, a possible critical regulator of apoptosis in rat pheochromocytoma PC12 cells

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Kainate receptor-mediated apoptosis in primary cultures of cerebellar granule cells is attenuated by mitogen-activated protein and cyclin-dependent kinase inhibitors

1 reference

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7 January 2021

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A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of thyroid hormone action

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequential up-regulation of thyroid hormone beta receptor, ornithine transcarbamylase, and carbamyl phosphate synthetase mRNAs in the liver of Rana catesbeiana tadpoles during spontaneous and thyroid hormone-induced metamorphosis

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Quiescence versus apoptosis: Myc abundance determines pathway of exit from the cell cycle

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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Expression profiles of novel thyroid hormone-responsive genes and proteins in the tail of Xenopus laevis tadpoles undergoing precocious metamorphosis.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Participation of cyclin A in Myc-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Genistein prevents thyroid hormone-dependent tail regression of Rana catesbeiana tadpoles by targetting protein kinase C and thyroid hormone receptor alpha.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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Cultured cells as a model for amphibian metamorphosis

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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Augmentation of thyroid hormone receptor-mediated transcription by Ca2+/calmodulin-dependent protein kinase type IV

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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Neuronal Cdc2-like kinase (Nclk) binds and phosphorylates the retinoblastoma protein.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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Apoptosis of central and peripheral neurons can be prevented with cyclin-dependent kinase/mitogen-activated protein kinase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of cyclin A-dependent protein kinases during apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Three cyclin-dependent kinases preferentially phosphorylate different parts of the C-terminal domain of the large subunit of RNA polymerase II.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Functional characterization of a mutant thyroid hormone receptor in Xenopus laevis

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin C/CDK8 and cyclin H/CDK7/p36 are biochemically distinct CTD kinases

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Coregulator codes of transcriptional regulation by nuclear receptors

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual functions of thyroid hormone receptors during Xenopus development

1 reference

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7 January 2021

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inferred from DOI database lookup

Complexities in the development of cyclin-dependent kinase inhibitor drugs

1 reference

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7 January 2021

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inferred from DOI database lookup

Roscovitine, a specific inhibitor of cellular cyclin-dependent kinases, inhibits herpes simplex virus DNA synthesis in the presence of viral early proteins

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Preclinical and clinical development of cyclin-dependent kinase modulators

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Premature p34cdc2 activation required for apoptosis.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased cyclin-dependent kinase activity promotes thyroid hormone-dependent tail regression in Rana catesbeiana

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

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An optimized freeze-squeeze method for the recovery of DNA fragments from agarose gels

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7 January 2021

based on heuristic

inferred from DOI database lookup

Stages in the normal development of Rana pipiens larvae.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Tissue-specific stabilization of the thyroid hormone beta1 nuclear receptor by phosphorylation

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of thyroid hormone receptors by protein kinase A regulates DNA recognition by specific inhibition of receptor monomer binding

1 reference

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7 January 2021

based on heuristic

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Detection of environmental endocrine-disruptor effects on gene expression in live Rana catesbeiana tadpoles using a tail fin biopsy technique

1 reference

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7 January 2021

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Distinctive gene profiles occur at key points during natural metamorphosis in the Xenopus laevis tadpole tail.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.21800

7 January 2021

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Expression of novel ING variants is regulated by thyroid hormone in the Xenopus laevis tadpole

1 reference

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7 January 2021

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1 reference

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7 January 2021

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Alteration of the phosphorylation state of p34cdc2 kinase by the flavone L86-8275 in breast carcinoma cells. Correlation with decreased H1 kinase activity

1 reference

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7 January 2021

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Xenopus laevis alpha and beta thyroid hormone receptors

1 reference

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7 January 2021

based on heuristic

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Physiological and molecular basis of thyroid hormone action

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Thyroid hormones and 3,5-diiodothyropropionic acid: new keys for new locks

1 reference

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1 reference

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