(Q51946283)

18 April 2018

title

Bile duct proliferation in Jag1/fringe heterozygous mice identifies candidate modifiers of the Alagille syndrome hepatic phenotype. (English)

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18 April 2018

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9

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author name string

Matthew J Ryan

1

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18 April 2018

Christina Bales

2

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Anthony Nelson

3

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Dorian M Gonzalez

4

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18 April 2018

Lara Underkoffler

5

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18 April 2018

Michelle Segalov

6

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18 April 2018

Jeanne Wilson-Rawls

7

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18 April 2018

Susan E Cole

8

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18 April 2018

Pierre Russo

10

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18 April 2018

Nancy B Spinner

11

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18 April 2018

Kenro Kusumi

12

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18 April 2018

Kathleen M Loomes

13

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18 April 2018

language of work or name

English

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publication date

1 December 2008

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18 April 2018

published in

Hepatology

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18 April 2018

volume

48

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issue

6

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18 April 2018

page(s)

1989-1997

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18 April 2018

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

cites work

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NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway

21 January 2018

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Mutations in the human Jagged1 gene are responsible for Alagille syndrome

21 January 2018

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Notch signaling: cell fate control and signal integration in development

21 January 2018

1 reference

An overview of the Notch signalling pathway

21 January 2018

1 reference

Jagged1 (JAG1) mutations in Alagille syndrome: increasing the mutation detection rate

21 January 2018

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Consequences of JAG1 mutations

21 January 2018

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Fringe is a glycosyltransferase that modifies Notch

21 January 2018

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Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2.

21 January 2018

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Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1

21 January 2018

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Glycosylation regulates Notch signalling.

21 January 2018

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Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

21 January 2018

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lunatic fringe is an essential mediator of somite segmentation and patterning

21 January 2018

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Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice

21 January 2018

1 reference

Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

21 January 2018

1 reference

Genetic modifiers in human development and malformation syndromes, including chaperone proteins

21 January 2018

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Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage.

21 January 2018

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The glycosyltransferase Fringe promotes Delta-Notch signaling between neurons and glia, and is required for subtype-specific glial gene expression

21 January 2018

1 reference

Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation

21 January 2018

1 reference

The role of notch signaling in the development of intrahepatic bile ducts

21 January 2018

1 reference

Inducible inactivation of Notch1 causes nodular regenerative hyperplasia in mice.

21 January 2018

1 reference

Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice.

21 January 2018

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Notch signaling regulates bile duct morphogenesis in mice

21 January 2018

1 reference

Characterization of Notch receptor expression in the developing mammalian heart and liver.

21 January 2018

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Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe

21 January 2018

1 reference

Features of Alagille syndrome in 92 patients: frequency and relation to prognosis

21 January 2018

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Lunatic fringe null female mice are infertile due to defects in meiotic maturation

21 January 2018

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Limbs move beyond the Radical fringe

21 January 2018

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A mutation in the Lunatic fringe gene suppresses the effects of a Jagged2 mutation on inner hair cell development in the cochlea

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Evidence for the epithelial to mesenchymal transition in biliary atresia fibrosis

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Notch receptor expression in adult human liver: a possible role in bile duct formation and hepatic neovascularization

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/HEP.22538

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18 April 2018

PubMed ID

19026002

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18 April 2018