(Q51997239)

19 April 2018

title

Activation-threshold tuning in an affinity model for the T-cell repertoire. (English)

1 reference

19 April 2018

author name string

Almut Scherer

series ordinal

1

1 reference

19 April 2018

André Noest

series ordinal

2

1 reference

19 April 2018

Rob J de Boer

series ordinal

3

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19 April 2018

publication date

1 March 2004

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19 April 2018

number of pages

8

1 reference

Proceedings of the Royal Society B

inferred from page(s)

published in

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19 April 2018

volume

271

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19 April 2018

issue

1539

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19 April 2018

page(s)

609-616

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19 April 2018

Selection and fine-tuning of the autoimmune T-cell repertoire

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22 May 2018

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Dynamic tuning of T cell reactivity by self-peptide-major histocompatibility complex ligands

22 May 2018

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Negative selection during the peripheral immune response to antigen

22 May 2018

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T cell receptor (TCR)-mediated repertoire selection and loss of TCR vbeta diversity during the initiation of a CD4(+) T cell response in vivo

22 May 2018

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22 May 2018

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22 May 2018

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Deriving quantitative constraints on T cell selection from data on the mature T cell repertoire

22 May 2018

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The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

22 May 2018

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How specific should immunological memory be?

22 May 2018

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Explaining high alloreactivity as a quantitative consequence of affinity-driven thymocyte selection

22 May 2018

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T cell affinity maturation by selective expansion during infection

22 May 2018

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Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells

22 May 2018

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Positive selection of low responsive, potentially autoreactive T cells induced by high avidity, non-deleting interactions.

22 May 2018

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Evolution of a complex T cell receptor repertoire during primary and recall bacterial infection

22 May 2018

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Deriving shape space parameters from immunological data

22 May 2018

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Quantitative impact of thymic clonal deletion on the T cell repertoire

22 May 2018

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Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

22 May 2018

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A differential-avidity model for T-cell selection

22 May 2018

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The E-T (elephant-tadpole) paradox necessitates the concept of a unit of B-cell function: the protection

22 May 2018

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Size and connectivity as emergent properties of a developing immune network

22 May 2018

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Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

22 May 2018

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Theoretical studies of clonal selection: Minimal antibody repertoire size and reliability of self-non-self discrimination

22 May 2018

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Memorizing innate instructions requires a sufficiently specific adaptive immune system.

22 May 2018

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A novel approach to the analysis of specificity, clonality, and frequency of HIV-specific T cell responses reveals a potential mechanism for control of viral escape.

13 August 2018

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T cells down-modulate peptide-MHC complexes on APCs in vivo.

13 August 2018

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The geometry of shape space: application to influenza.

13 August 2018

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A reliable and safe T cell repertoire based on low-affinity T cell receptors.

13 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1691638

A quantitative theory of affinity-driven T cell repertoire selection.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1691638

Tolerant CD8 T cells induced by multiple injections of peptide antigen show impaired TCR signaling and altered proliferative responses in vitro and in vivo

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1691638

Size and connectivity of the idiotypic network are independent of the discreteness of the affinity distribution

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1691638

Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion

13 August 2018

1 reference

12 December 2020

Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

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12 December 2020

Tuning T cell activation threshold and effector function with cross-reactive peptide ligands

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12 December 2020

Diversity of human alpha beta T cell receptors

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12 December 2020

Designing lymphocyte functional structure for optimal signal detection: voilà, T cells

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12 December 2020

How diverse should the immune system be?

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12 December 2020

Agonist peptide modulates T cell selection thresholds through qualitative and quantitative shifts in CD8 co-receptor expression

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12 December 2020

Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire

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12 December 2020

Identifiers

DOI

10.1098/RSPB.2003.2653

1 reference

19 April 2018

PMCID

1691638

1 reference

19 April 2018

PubMed ID

15156919

1 reference

19 April 2018