(Q52085313)

21 April 2018

title

Temporal modulation of the Hedgehog morphogen gradient by a patched-dependent targeting to lysosomal compartment. (English)

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21 April 2018

author name string

Armel Gallet

series ordinal

1

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21 April 2018

Pascal P Therond

series ordinal

2

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21 April 2018

language of work or name

English

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publication date

1 January 2005

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21 April 2018

published in

Developmental Biology

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21 April 2018

volume

277

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21 April 2018

issue

1

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21 April 2018

page(s)

51-62

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21 April 2018

Posttranscriptional regulation of smoothened is part of a self-correcting mechanism in the Hedgehog signaling system

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

A hedgehog-insensitive form of patched provides evidence for direct long-range morphogen activity of sonic hedgehog in the neural tube.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Dual roles for patched in sequestering and transducing Hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Regulated endocytic routing modulates wingless signaling in Drosophila embryos.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Gradient formation of the TGF-beta homolog Dpp.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Structural conservation of Notch receptors and ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Divide and conquer: pattern formation in Drosophila embryonic epidermis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Drosophila hedgehog acts as a morphogen in cellular patterning.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Sonic hedgehog induces the segregation of patched and smoothened in endosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Hrs mediates downregulation of multiple signalling receptors in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Cholesterol modification of Hedgehog family proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

patched overexpression causes loss of wingless expression in Drosophila embryos.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Patched acts catalytically to suppress the activity of Smoothened

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

A freely diffusible form of Sonic hedgehog mediates long-range signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

Rab proteins as membrane organizers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.09.005

10.1016/J.YDBIO.2004.09.005

7 January 2021

Identifiers

DOI

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21 April 2018

PubMed ID

15572139

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21 April 2018