(Q52086491)

21 April 2018

title

Tissue inhibitor of metalloproteinase-2 (TIMP-2) expression during cardiac neural crest cell migration and its role in proMMP-2 activation. (English)

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21 April 2018

author name string

Cantemir V

1

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21 April 2018

Cai DH

2

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21 April 2018

Reedy MV

3

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21 April 2018

Brauer PR

4

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21 April 2018

publication date

1 December 2004

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21 April 2018

published in

Developmental Dynamics

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21 April 2018

volume

231

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21 April 2018

issue

4

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21 April 2018

page(s)

709-719

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21 April 2018

TGF-beta3-induced palatogenesis requires matrix metalloproteinases

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The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study

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MMP-2 expression during early avian cardiac and neural crest morphogenesis

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Inactivating mutation of the mouse tissue inhibitor of metalloproteinases-2(Timp-2) gene alters proMMP-2 activation

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Specialized surface protrusions of invasive cells, invadopodia and lamellipodia, have differential MT1-MMP, MMP-2, and TIMP-2 localization

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Decreased neural crest stem cell expansion is responsible for the conotruncal heart defects within the splotch (Sp(2H))/Pax3 mouse mutant

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MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells

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Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model

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Structural and functional uncoupling of the enzymatic and angiogenic inhibitory activities of tissue inhibitor of metalloproteinase-2 (TIMP-2): loop 6 is a novel angiogenesis inhibitor

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7 January 2021

Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation.

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Plasticity and predetermination of mesencephalic and trunk neural crest transplanted into the region of the cardiac neural crest

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7 January 2021

Neural crest cells contribute to normal aorticopulmonary septation

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7 January 2021

Tumor targeting with a selective gelatinase inhibitor

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7 January 2021

Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes

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7 January 2021

Epidermal growth factor receptor function is necessary for normal craniofacial development and palate closure

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7 January 2021

Cellular activation of MMP-2 (gelatinase A) by MT2-MMP occurs via a TIMP-2-independent pathway

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7 January 2021

Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion

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7 January 2021

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7 January 2021

Age-dependent inhibition of neural crest migration by the notochord correlates with alterations in the S103L chondroitin sulfate proteoglycan

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7 January 2021

Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma

1 reference

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7 January 2021

MT1-MMP correlates with MMP-2 activation potential seen after epithelial to mesenchymal transition in human breast carcinoma cells.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

Different susceptibility of small and large human tenascin-C isoforms to degradation by matrix metalloproteinases.

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7 January 2021

Degradation of type IV collagen by matrix metalloproteinases is an important step in the epithelial-mesenchymal transformation of the endocardial cushions

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (Membrane type 1)-MMP-dependent activation of pro-MMP-2.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

Membrane proteases in focus

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

TIMP-2 is required for efficient activation of proMMP-2 in vivo

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

Extracellular matrix remodeling during morphogenesis.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis

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https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

The expression of tissue inhibitor of metalloproteinase 2 (TIMP-2) is required for normal development of zebrafish embryos

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

Tissue inhibitor of metalloproteinase-2 (TIMP-2) binds to the catalytic domain of the cell surface receptor, membrane type 1-matrix metalloproteinase 1 (MT1-MMP)

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.20171

7 January 2021

Identifiers

DOI

10.1002/DVDY.20171

1 reference

21 April 2018

1 reference

21 April 2018