(Q52151966)

23 April 2018

title

Early intervention with glucagon-like peptide 1 analog liraglutide prevents tau hyperphosphorylation in diabetic db/db mice. (English)

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23 April 2018

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De-Lin Ma

1

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23 April 2018

Fu-Qiong Chen

2

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23 April 2018

Wei-Jie Xu

3

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23 April 2018

Wen-Zhu Yue

4

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23 April 2018

Gang Yuan

5

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23 April 2018

Yan Yang

6

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23 April 2018

language of work or name

English

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publication date

16 July 2015

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23 April 2018

Journal of Neurochemistry

published in

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23 April 2018

volume

135

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23 April 2018

issue

2

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23 April 2018

page(s)

301-308

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23 April 2018

Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease.

cites work

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Effects of antidiabetic treatment with metformin and insulin on serum and adipose tissue adiponectin levels in db/db mice

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Potential role of glucagon-like peptide-1 (GLP-1) in neuroprotection

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Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis

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Selectively silencing GSK-3 isoforms reduces plaques and tangles in mouse models of Alzheimer's disease

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Tau in Alzheimer disease and related tauopathies

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Age-dependent increases in tau phosphorylation in the brains of type 2 diabetic rats correlate with a reduced expression of p62.

21 January 2018

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Hyperinsulinemia in rats causes impairment of spatial memory and learning with defects in hippocampal synaptic plasticity by involvement of postsynaptic mechanisms.

21 January 2018

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Increased tau phosphorylation and cleavage in mouse models of type 1 and type 2 diabetes.

21 January 2018

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Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice

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Metformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice

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Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease

21 January 2018

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Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

21 January 2018

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Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer's disease.

21 January 2018

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A biochemical and functional characterization of diet-induced brain insulin resistance

21 January 2018

1 reference

Chronic treatment with the GLP1 analogue liraglutide increases cell proliferation and differentiation into neurons in an AD mouse model

21 January 2018

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GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

21 January 2018

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Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone.

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Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice.

21 January 2018

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Neurobehavioral deficits in db/db diabetic mice

21 January 2018

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Neuroprotective and anti-apoptotic effects of liraglutide on SH-SY5Y cells exposed to methylglyoxal stress

21 January 2018

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Effect of intranasal insulin on cognitive function: a systematic review

21 January 2018

1 reference

The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes

21 January 2018

1 reference

Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer's pathology and APOE genotype.

21 January 2018

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Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

21 January 2018

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21 January 2018

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Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes.

21 January 2018

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Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: possible involvement of cholinergic and VEGF/PDGF mechanisms in the brain

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JNC.13248

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23 April 2018

PubMed ID

26183127

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23 April 2018