(Q52195700)

English

Tachykinin NK1 receptor antagonist RP67580 attenuates progressive hypersensitivity of flexor reflex during experimental inflammation in rats.

scientific article published in March 1997

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

Tachykinin NK1 receptor antagonist RP67580 attenuates progressive hypersensitivity of flexor reflex during experimental inflammation in rats. (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

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tachykinin receptor

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Clifford J. Woolf

2

object named as

C J Woolf

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Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

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Q P Ma

1

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Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

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publication date

1 March 1997

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Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

European Journal of Pharmacology

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Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

322

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

2-3

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

165-171

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

The effect of intrathecal administration of RP67580, a potent neurokinin 1 antagonist on nociceptive transmission in the rat spinal cord

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Comparison of the effects of substance P, neurokinin A, physalaemin and eledoisin in facilitating a nociceptive reflex in the rat.

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Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

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Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurons in vivo by noxious stimulation

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Increased expression of preprotachykinin, calcitonin gene-related peptide, but not vasoactive intestinal peptide messenger RNA in dorsal root ganglia during the development of adjuvant monoarthritis in the rat.

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Increased content and transport of substance P and calcitonin gene-related peptide in sensory nerves innervating inflamed tissue: Evidence for a regulatory function of nerve growth factor in vivo

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Cutaneous stimuli releasing immunoreactive substance P in the dorsal horn of the cat

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Enhanced release of immunoreactive CGRP and substance P from spinal dorsal horn slices occurs during carrageenan inflammation

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The proportion of CGRP-immunoreactive and SP-mRNA containing dorsal root ganglion cells is increased by a unilateral inflammation of the ankle joint of the rat

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Substance P: Localization in the Central Nervous System and in Some Primary Sensory Neurons

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Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridization

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Dorsal root ganglion neurons are destroyed by exposure in utero to maternal antibody to nerve growth factor

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Pre-emptive lumbar epidural anaesthesia reduces postoperative pain and patient-controlled morphine consumption after lower abdominal surgery.

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Effects of morphine on noxious stimuli-induced release of substance P from rabbit dorsal horn

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Calcitonin gene-related peptide increases in the dorsal root ganglia of adjuvant arthritic rat

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Nerve growth factor regulates expression of neuropeptide genes in adult sensory neurons

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Neuropeptide expression in cultures of adult sensory neurons: modulation of substance P and calcitonin gene-related peptide levels by nerve growth factor

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Involvement of neurokinin receptors in the induction but not the maintenance of mechanical allodynia in rat flexor motoneurones.

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7 January 2021

Noxious stimuli induce an N-methyl-D-aspartate receptor-dependent hypersensitivity of the flexion withdrawal reflex to touch: implications for the treatment of mechanical allodynia.

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Progressive tactile hypersensitivity: an inflammation-induced incremental increase in the excitability of the spinal cord

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Monoarthritis in the rat knee induces bilateral and time-dependent changes in substance P and calcitonin gene-related peptide immunoreactivity in the spinal cord

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Peptide immunoreactivity of unmyelinated primary afferent axons in rat lumbar dorsal roots

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7 January 2021

Actions of substance P on rat spinal dorsal horn neurones.

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The role of neurokinin and N-methyl-D-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro

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7 January 2021

NK1 and NK2 receptors contribute to C-fibre evoked slow potentials in the spinal cord.

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A noxious stimulus induces the preprotachykinin-A gene expression in the rat dorsal root ganglion: a quantitative study using in situ hybridization histochemistry

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Dynorphin expression and Fos-like immunoreactivity following inflammation induced hyperalgesia are colocalized in spinal cord neurons

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Preproenkephalin mRNA in spinal dorsal horn neurons is induced by peripheral inflammation and is co-localized with Fos and Fos-related proteins

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Use of non-peptide tachykinin receptor antagonists to substantiate the involvement of NK1 and NK2 receptors in a spinal nociceptive reflex in the rat.

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Intracellular responses of dorsal horn cells to cutaneous and sural nerve A and C fiber stimuli

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Preoperative morphine pre-empts postoperative pain

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Selective dependence of mammalian dorsal root ganglion neurons on nerve growth factor during embryonic development.

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Inflammation-induced upregulation of NK1 receptor mRNA in dorsal horn neurones

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Effects of an experimental arthritis on the sensory properties of fine articular afferent units

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Sensitization of cat dorsal horn neurons to innocuous mechanical stimulation after intradermal injection of capsaicin

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The contribution of GABAA and glycine receptors to central sensitization: disinhibition and touch-evoked allodynia in the spinal cord.

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Increase in substance P and CGRP, but not somatostatin content of innervating dorsal root ganglia in adjuvant monoarthritis in the rat

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Time-dependent changes in Bolton-Hunter-labeled 125I-substance P binding in rat spinal cord following unilateral adjuvant-induced peripheral inflammation

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Long duration ventral root potentials in the neonatal rat spinal cord in vitro; the effects of ionotropic and metabotropic excitatory amino acid receptor antagonists

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Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans

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Slow excitatory transmission in rat dorsal horn: possible mediation by peptides

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Muscle but not cutaneous C-afferent input produces prolonged increases in the excitability of the flexion reflex in the rat.

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Substance P and somatostatin modulate spinal cord excitability via physiologically different sensory pathways

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The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states

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Relative effectiveness of C primary afferent fibers of different origins in evoking a prolonged facilitation of the flexor reflex in the rat.

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Substance P and calcitonin gene-related peptide synergistically modulate the gain of the nociceptive flexor withdrawal reflex in the rat

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Nerve growth factor contributes to the generation of inflammatory sensory hypersensitivity.

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Sensitization of high mechanothreshold superficial dorsal horn and flexor motor neurones following chemosensitive primary afferent activation.

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Identifiers

10.1016/S0014-2999(97)00014-9

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 April 2018

http://europepmc.org/abstract/MED/9098683

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