(Q52338093)

English

Effects of insulin concentration and self-association on the partitioning of its A-21 cyclic anhydride intermediate to desamido insulin and covalent dimer.

scientific article published in July 1995

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

Effects of insulin concentration and self-association on the partitioning of its A-21 cyclic anhydride intermediate to desamido insulin and covalent dimer. (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

author name string

R T Darrington

1

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

B D Anderson

2

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

publication date

1 July 1995

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

12

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

7

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

1077-1084

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

Stability of interleukin 1 beta (IL-1 beta) in aqueous solution: analytical methods, kinetics, products, and solution formulation implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

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Comparative study of biosynthetic human growth hormone immunogenicity in growth hormone deficient children

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1H NMR spectrum of the native human insulin monomer. Evidence for conformational differences between the monomer and aggregated forms

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-metal ion interactions: the binding of divalent cations to insulin hexamers and tetramers and the assembly of insulin hexamers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble, prolonged-acting insulin derivatives. III. Degree of protraction, crystallizability and chemical stability of insulins substituted in positions A21, B13, B23, B27 and B30

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent cutaneous insulin allergy resulting from high-molecular-weight insulin aggregates

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The source of the circulating aggregate of insulin in type I diabetic patients is therapeutic insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of aggregated human growth hormone (hGH) in development of antibodies to hGH

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of 2Zn pig insulin crystals at 1.5 A resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical, physical, and biological characterization of a dimeric form of biosynthetic human growth hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lyophilized formulations of recombinant tumor necrosis factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An equilibrium ultracentrifuge study of the self-association of bovine insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical stability of insulin. 3. Influence of excipients, formulation, and pH

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a common intermediate in insulin deamidation and covalent dimer formation: effects of pH and aniline trapping in dilute acidic solutions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational flexibility of aqueous monomeric and dimeric insulin: a molecular dynamics study

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The thermodynamics of bovine and porcine insulin and proinsulin association determined by concentration difference spectroscopy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design, synthesis, and testing of insulin hexamer-stabilizing agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The self-association of zinc-free human insulin and insulin analogue B13-glutamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stability of beta-galactosidase, a model protein drug, is related to water mobility as measured by 17O nuclear magnetic resonance (NMR).

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of freezing on aggregation of human growth hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical stability of insulin. 5. Isolation, characterization and identification of insulin transformation products

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship of structure to biological activity of insulin as revealed by degradative studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nature of aggregates formed during storage of freeze-dried ribonuclease A

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies to covalent aggregates of insulin in blood of insulin-using diabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of intramolecular nucleophilic catalysis and the effects of self-association on the deamidation of human insulin at low pH

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin self-association. Spectrum changes and thermodynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc binding, circular dichroism, and equilibrium sedimentation studies on insulin (bovine) and several of its derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional atomic structure of insulin and its relationship to activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1H Fourier transform NMR studies of insulin: coordination of Ca2+ to the Glu(B13) site drives hexamer assembly and induces a conformation change

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical stability of insulin. 2. Formation of higher molecular weight transformation products during storage of pharmaceutical preparations

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural stability in the 4-zinc human insulin hexamer

1 reference

https://pubmed.ncbi.nlm.nih.gov/7494806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1016231019677

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 April 2018

http://europepmc.org/abstract/MED/7494806

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