(Q52430975)

http://europepmc.org/abstract/MED/29570986

1 May 2018

title

AMPK Phosphorylation of ACE2 in Endothelium Mitigates Pulmonary Hypertension. (English)

1 reference

http://europepmc.org/abstract/MED/29570986

1 May 2018

0 references

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Jiao Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Jianjie Dong

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Marcy Martin

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Ming He

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Brendan Gongol

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Traci L Marin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Lili Chen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Xinxing Shi

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Yanjun Yin

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Fenqing Shang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Yan Wu

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Hsi-Yuan Huang

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Jin Zhang

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Yu Zhang

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Jian Kang

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Esteban A Moya

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Hsien-Da Huang

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Frank L Powell

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Zhen Chen

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Patricia A Thistlethwaite

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

John Y-J Shyy

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

language of work or name

English

0 references

publication date

23 March 2018

1 reference

http://europepmc.org/abstract/MED/29570986

1 May 2018

published in

American Journal of Respiratory and Critical Care Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

198

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

509-520

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

The sirtuin 6 prevents angiotensin II-mediated myocardial fibrosis and injury by targeting AMPK-ACE2 signaling

8 June 2020

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1 reference

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4 October 2018

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Hypermethylation of BMPR2 Promoter Occurs in Patients with Heritable Pulmonary Arterial Hypertension and Inhibits BMPR2 Expression.

4 October 2018

1 reference

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AMP-Activated Protein Kinase and Sirtuin 1 Coregulation of Cortactin Contributes to Endothelial Function

4 October 2018

1 reference

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Genetic Insights into Pulmonary Arterial Hypertension. Application of Whole-Exome Sequencing to the Study of Pathogenic Mechanisms

4 October 2018

1 reference

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Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension.

4 October 2018

1 reference

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Update in Pulmonary Vascular Disease 2015.

4 October 2018

1 reference

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Protective Roles of Endothelial AMP-Activated Protein Kinase Against Hypoxia-Induced Pulmonary Hypertension in Mice.

4 October 2018

1 reference

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Role of the ACE2/Angiotensin 1-7 Axis of the Renin-Angiotensin System in Heart Failure

4 October 2018

1 reference

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SIRT3-AMP-Activated Protein Kinase Activation by Nitrite and Metformin Improves Hyperglycemia and Normalizes Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction

4 October 2018

1 reference

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Endothelin-1 Pathway Polymorphisms and Outcomes in Pulmonary Arterial Hypertension

4 October 2018

1 reference

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Identification of AMP-activated protein kinase targets by a consensus sequence search of the proteome

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Angiotensin II mediates angiotensin converting enzyme type 2 internalization and degradation through an angiotensin II type I receptor-dependent mechanism.

4 October 2018

1 reference

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Angiotensin-converting enzyme 2 and angiotensin 1-7: novel therapeutic targets

4 October 2018

1 reference

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Regulatory effect of AMP-activated protein kinase on pulmonary hypertension induced by chronic hypoxia in rats: in vivo and in vitro studies.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Prolonged hypoxia increases survival even in Zebrafish (Danio rerio) showing cardiac arrhythmia

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

AMPKα2 exerts its anti-inflammatory effects through PARP-1 and Bcl-6.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Bone morphogenetic protein receptor II is a novel mediator of endothelial nitric-oxide synthase activation

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

The interaction between endothelin-1 and nitric oxide in the vasculature: new perspectives.

4 October 2018

1 reference

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AMPK and vasculoprotection

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Notch3 signaling promotes the development of pulmonary arterial hypertension

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Protective role of the antidiabetic drug metformin against chronic experimental pulmonary hypertension.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Endothelin-1 impairs nitric oxide signaling in endothelial cells through a protein kinase Cdelta-dependent activation of STAT3 and decreased endothelial nitric oxide synthase expression

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Identification, analysis, and prediction of protein ubiquitination sites

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Activation and signaling by the AMP-activated protein kinase in endothelial cells

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Cellular and molecular basis of pulmonary arterial hypertension

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

4 October 2018

1 reference

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Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.

4 October 2018

1 reference

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AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633

4 October 2018

1 reference

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Endothelial cell dysfunction and cross talk between endothelium and smooth muscle cells in pulmonary arterial hypertension.

4 October 2018

1 reference

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Downregulation by lipopolysaccharide of Notch signaling, via nitric oxide

4 October 2018

1 reference

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Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)-Mas axis.

4 October 2018

1 reference

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The age of crosstalk: phosphorylation, ubiquitination, and beyond

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Pulmonary arterial hypertension: a disease of tethers, SNAREs and SNAPs?

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

VEGF regulation of endothelial nitric oxide synthase in glomerular endothelial cells

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Estradiol-mediated endothelial nitric oxide synthase association with heat shock protein 90 requires adenosine monophosphate-dependent protein kinase.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Retroviruses pseudotyped with the severe acute respiratory syndrome coronavirus spike protein efficiently infect cells expressing angiotensin-converting enzyme 2.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Dissection of c-MOS degron

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure.

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Role of AMP-activated protein kinase in mechanism of metformin action

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase

4 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6118028

Angiotensin-(1-7) inhibits vascular smooth muscle cell growth

4 October 2018

1 reference

12 December 2020

Primary pulmonary hypertension

1 reference

12 December 2020

Hypoxic pulmonary vasoconstriction

1 reference

12 December 2020

The changes of serum angiotensin-converting enzyme 2 in patients with pulmonary arterial hypertension due to congenital heart disease

1 reference

12 December 2020

10.1164/RCCM.201712-2570OC

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29570986%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference