(Q52568575)

3 May 2018

title

A brief history of autophagy from cell biology to physiology and disease. (English)

1 reference

3 May 2018

1 reference

1 reference

1 reference

1

1 reference

3 May 2018

publication date

23 April 2018

1 reference

3 May 2018

published in

Nature Cell Biology

1 reference

3 May 2018

volume

20

1 reference

3 May 2018

issue

5

1 reference

3 May 2018

page(s)

521-527

1 reference

3 May 2018

https://scigraph.springernature.com/pub.10.1038/s41556-018-0092-5

exact match

0 references

cites work

In praise of M. Anselmier who first used the term "autophagie" in 1859.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy revisited: a conversation with Christian de Duve

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy: renovation of cells and tissues

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Cargo recognition and trafficking in selective autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Cargo recognition and degradation by selective autophagy.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy fights disease through cellular self-digestion

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Chaperone-mediated autophagy and endosomal microautophagy: joint by a chaperone

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Intracellular protein catabolism and its control during nutrient deprivation and supply

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Regulation and role of autophagy in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Sequestration revisited: integrating traditional electron microscopy, de novo assembly and new results

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

The versatile electron microscope: an ultrastructural overview of autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Isolation of autophagocytosis mutants of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Peroxisome degradation by microautophagy in Pichia pastoris: identification of specific steps and morphological intermediates

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Isolation and characterization of mutants impaired in the selective degradation of peroxisomes in the yeast Hansenula polymorpha

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

A Unified Nomenclature for Yeast Autophagy-Related Genes

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

A newly characterized vacuolar serine carboxypeptidase, Atg42/Ybr139w, is required for normal vacuole function and the terminal steps of autophagy in the yeast Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Dynamics and diversity in autophagy mechanisms: lessons from yeast

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

C. elegans screen identifies autophagy genes specific to multicellular organisms

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

The role of Atg proteins in autophagosome formation

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagic tubes: vacuolar invaginations involved in lateral membrane sorting and inverse vesicle budding

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Modification of a ubiquitin-like protein Paz2 conducted micropexophagy through formation of a novel membrane structure

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Piecemeal microautophagy of the nucleus requires the core macroautophagy genes.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

A sterol-enriched vacuolar microdomain mediates stationary phase lipophagy in budding yeast

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Lipid droplet autophagy in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Microautophagy of cytosolic proteins by late endosomes

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

ESCRTs Cooperate with a Selective Autophagy Receptor to Mediate Vacuolar Targeting of Soluble Cargos

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Evidence for ESCRT- and clathrin-dependent microautophagy.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Selective endosomal microautophagy is starvation-inducible in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Peptide sequences that target cytosolic proteins for lysosomal proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

A receptor for the selective uptake and degradation of proteins by lysosomes

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

The role of autophagy during the early neonatal starvation period

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy is essential for preimplantation development of mouse embryos.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Neuronal aggregates: formation, clearance, and spreading

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Loss of autophagy in the central nervous system causes neurodegeneration in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Cleaning House: Selective Autophagy of Organelles

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Self and nonself: how autophagy targets mitochondria and bacteria

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Exome sequencing reveals de novo WDR45 mutations causing a phenotypically distinct, X-linked dominant form of NBIA.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy genes are essential for dauer development and life-span extension in C. elegans

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Can autophagy promote longevity?

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Metabolic Control of Longevity.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy-deficient mice develop multiple liver tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Recent insights into the function of autophagy in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

The mammalian ULK1 complex and autophagy initiation.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy in the context of the cellular membrane-trafficking system: the enigma of Atg9 vesicles

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Ultrastructural analysis of autophagosome organization using mammalian autophagy-deficient cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

The late stages of autophagy: how does the end begin?

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

The ATG conjugation systems are important for degradation of the inner autophagosomal membrane.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Atg8 family LC3/GABARAP proteins are crucial for autophagosome-lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Studies on the mechanisms of autophagy: formation of the autophagic vacuole

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

A cluster of thin tubular structures mediates transformation of the endoplasmic reticulum to autophagic isolation membrane

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

3D tomography reveals connections between the phagophore and endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

ER exit sites are physical and functional core autophagosome biogenesis components

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

The ER-Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagosomes form at ER-mitochondria contact sites

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

ER-plasma membrane contact sites contribute to autophagosome biogenesis by regulation of local PI3P synthesis

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagosome formation is initiated at phosphatidylinositol synthase-enriched ER subdomains

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Atg8-family interacting motif crucial for selective autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Structural and functional analysis of the GABARAP interaction motif (GIM).

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Receptor-Bound Targets of Selective Autophagy Use a Scaffold Protein to Activate the Atg1 Kinase

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Transition from Complete to Partial Wetting within Membrane Compartments

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Liquid phase condensation in cell physiology and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Germline P granules are liquid droplets that localize by controlled dissolution/condensation

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Genetic visualization of protein interactions harnessing liquid phase transitions

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

p62 filaments capture and present ubiquitinated cargos for autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Sensing Membrane Curvature in Macroautophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

CapZ regulates autophagosomal membrane shaping by promoting actin assembly inside the isolation membrane

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Shape transformations of vesicles: Phase diagram for spontaneous- curvature and bilayer-coupling models

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Curvature of double-membrane organelles generated by changes in membrane size and composition

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Sphingomyelin metabolism controls the shape and function of the Golgi cisternae

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagosome closure requires membrane scission

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

The coordination of membrane fission and fusion at the end of autophagosome maturation

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy-monitoring and autophagy-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Mitochondrial division occurs concurrently with autophagosome formation but independently of Drp1 during mitophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Discovery of Atg5/Atg7-independent alternative macroautophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Unconventional protein secretion: an evolving mechanism

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

1 reference

7 January 2021

To be or not to be? How selective autophagy and cell death govern cell fate

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Beyond self-eating: The control of nonautophagic functions and signaling pathways by autophagy-related proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Hidden behind autophagy: the unconventional roles of ATG proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Methods in mammalian autophagy research

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Development of autophagy inducers in clinical medicine

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy: A Druggable Process

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Induction of autophagy by amino-acid deprivation in perfused rat liver

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Inhibition by insulin of the formation of autophagic vacuoles in rat liver. A morphometric approach to the kinetics of intracellular degradation by autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

A protein conjugation system essential for autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

A ubiquitin-like system mediates protein lipidation

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Autophagy defends cells against invading group A Streptococcus

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

TFEB links autophagy to lysosomal biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

Recessive mutations in EPG5 cause Vici syndrome, a multisystem disorder with defective autophagy.

1 reference

https://api.crossref.org/works/10.1038%2FS41556-018-0092-5

7 January 2021

10.1038/S41556-018-0092-5

Identifiers

DOI

1 reference

3 May 2018

1 reference

3 May 2018