(Q52568671)

http://europepmc.org/abstract/PMC/5949003

23 June 2018

title

Prevention of hepatocellular carcinoma by targeting MYCN-positive liver cancer stem cells with acyclic retinoid. (English)

1 reference

http://europepmc.org/abstract/PMC/5949003

23 June 2018

main subject

neoplastic stem cells

1 reference

1 reference

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Piero Carninci

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Kan Toriguchi

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

17

Etsuro Hatano

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

11

Hideki Tatsukawa

1 reference

11 June 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

1

Xian-Yang Qin

1 reference

11 June 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

2

Harukazu Suzuki

1 reference

11 June 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

6

Ikuyo Inoue

1 reference

11 June 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

Masao Honda

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Hikari Okada

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Shuichi Kaneko

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Etsuko Ebisui

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Kosuke Hashimoto

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Keita Kanki

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Naoto Ishibashi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Takahiro Masaki

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Tomokazu Matsuura

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Hiroyuki Kagechika

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Yohei Shirakami

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Goshi Shiota

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Masahito Shimizu

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Hisataka Moriwaki

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

23 April 2018

1 reference

http://europepmc.org/abstract/PMC/5949003

23 June 2018

published in

Proceedings of the National Academy of Sciences of the United States of America

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

4969-4974

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

11 June 2020

copyright license

start time

23 April 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on Hepatocytes

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Molecular mechanism by which acyclic retinoid induces nuclear localization of transglutaminase 2 in human hepatocellular carcinoma cells

24 June 2018

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CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors.

24 June 2018

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Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis

24 June 2018

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24 June 2018

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Survey of survival among patients with hepatitis C virus-related hepatocellular carcinoma treated with peretinoin, an acyclic retinoid, after the completion of a randomized, placebo-controlled trial

24 June 2018

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Drugging MYCN through an allosteric transition in Aurora kinase A

24 June 2018

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Peretinoin after curative therapy of hepatitis C-related hepatocellular carcinoma: a randomized double-blind placebo-controlled study

24 June 2018

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The role of cell density and intratumoral heterogeneity in multidrug resistance

24 June 2018

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Biological and clinical implications of retinoic acid-responsive genes in human hepatocellular carcinoma cells

24 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

24 June 2018

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Peretinoin, an acyclic retinoid, improves the hepatic gene signature of chronic hepatitis C following curative therapy of hepatocellular carcinoma

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Acyclic retinoid in chemoprevention of hepatocellular carcinoma: Targeting phosphorylated retinoid X receptor-α for prevention of liver carcinogenesis

24 June 2018

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24 June 2018

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MYC on the path to cancer

24 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

24 June 2018

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Maintaining embryonic stem cell pluripotency with Wnt signaling

24 June 2018

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Hallmarks of Cancer: The Next Generation

24 June 2018

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Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells

24 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

The incidence and epidemiology of hepatocellular carcinoma: a global and regional perspective

24 June 2018

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Acyclic retinoid inhibits diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BLKS/J- +(db)/+Lepr(db) mice

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Role of transglutaminase 2 in liver injury via cross-linking and silencing of transcription factor Sp1

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Liver stem cells and hepatocellular carcinoma

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

24 June 2018

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Identification and characterization of tumorigenic liver cancer stem/progenitor cells

24 June 2018

1 reference

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Transdifferentiation of hepatocyte-like cells from the human hepatoma HepaRG cell line through bipotent progenitor.

24 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide

24 June 2018

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24 June 2018

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E2F and Sp1/Sp3 Synergize but are not sufficient to activate the MYCN gene in neuroblastomas.

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Molecular mechanism for growth suppression of human hepatocellular carcinoma cells by acyclic retinoid

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Neuroblastoma: biological insights into a clinical enigma

24 June 2018

1 reference

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Prevention of chemical carcinogenesis by vitamin A and its synthetic analogs (retinoids)

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Metabolome Analyses Uncovered a Novel Inhibitory Effect of Acyclic Retinoid on Aberrant Lipogenesis in a Mouse Diethylnitrosamine-Induced Hepatic Tumorigenesis Model.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

The CD133+CD44+ precancerous subpopulation of oval cells is a therapeutic target for hepatocellular carcinoma.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Cancer stem cell definitions and terminology: the devil is in the details.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Prevention of rat hepatocarcinogenesis by acyclic retinoid is accompanied by reduction in emergence of both TGF-alpha-expressing oval-like cells and activated hepatic stellate cells

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5949003

Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma. Hepatoma Prevention Study Group

13 August 2018

1 reference

12 December 2020

Deletion of serum lectin-reactive alpha-fetoprotein by acyclic retinoid: a potent biomarker in the chemoprevention of second primary hepatoma

1 reference

12 December 2020

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

12 December 2020

Different risk factors and prognosis for early and late intrahepatic recurrence after resection of hepatocellular carcinoma

1 reference

12 December 2020

Prevention of recurrence after resection of hepatocellular carcinoma: a daunting challenge

1 reference

12 December 2020

Carboxylic Derivatives of Vitamin K2 Inhibit Hepatocellular Carcinoma Cell Growth through Caspase/Transglutaminase-Related Signaling Pathways

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1802279115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29686061%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

29686061

1 reference