(Q52568827)

3 May 2018

title

Modulation of the remote heme site geometry of recombinant mouse neuronal nitric-oxide synthase by the N-terminal hook region. (English)

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3 May 2018

author name string

Iwasaki T

1

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3 May 2018

Hori H

2

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3 May 2018

Hayashi Y

3

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3 May 2018

Nishino T

4

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3 May 2018

language of work or name

English

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publication date

1 March 1999

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3 May 2018

Journal of Biological Chemistry

published in

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3 May 2018

volume

274

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3 May 2018

issue

12

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3 May 2018

page(s)

7705-7713

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3 May 2018

Nitric oxide: a physiologic messenger molecule

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Tetrahydrobiopterin, a cofactor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine

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Endothelial nitric-oxide synthase. Expression in Escherichia coli, spectroscopic characterization, and role of tetrahydrobiopterin in dimer formation.

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Characterization of the inducible nitric oxide synthase oxygenase domain identifies a 49 amino acid segment required for subunit dimerization and tetrahydrobiopterin interaction

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Tetrahydrobiopterin binding to macrophage inducible nitric oxide synthase: heme spin shift and dimer stabilization by the potent pterin antagonist 4-amino-tetrahydrobiopterin.

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Domain swapping in inducible nitric-oxide synthase. Electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer.

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Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation

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The crucial roles of Asp-314 and Thr-315 in the catalytic activation of molecular oxygen by neuronal nitric-oxide synthase. A site-directed mutagenesis study.

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21 January 2018

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21 January 2018

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21 January 2018

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Cloning and characterization of human inducible nitric oxide synthase splice variants: a domain, encoded by exons 8 and 9, is critical for dimerization

21 January 2018

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Tetrahydrobiopterin-deficient nitric oxide synthase has a modified heme environment and forms a cytochrome P-420 analogue

21 January 2018

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Identification of nitric oxide synthase as a thiolate-ligated heme protein using magnetic circular dichroism spectroscopy. Comparison with cytochrome P-450-CAM and chloroperoxidase

21 January 2018

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Substrate binding-induced changes in the EPR spectra of the ferrous nitric oxide complexes of neuronal nitric oxide synthase

21 January 2018

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Purification to homogeneity and characterisation of rat brain recombinant nitric oxide synthase

21 January 2018

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Comparative functioning of dihydro- and tetrahydropterins in supporting electron transfer, catalysis, and subunit dimerization in inducible nitric oxide synthase

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.12.7705

1 reference

3 May 2018

PubMed ID

10075660

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3 May 2018