(Q52574173)

3 May 2018

title

Disruption of diacylglycerol metabolism impairs the induction of T cell anergy. (English)

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3 May 2018

author name string

Benjamin A Olenchock

1

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3 May 2018

Rishu Guo

2

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3 May 2018

Jeffery H Carpenter

3

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3 May 2018

Martha Jordan

4

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3 May 2018

Matthew K Topham

5

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3 May 2018

Gary A Koretzky

6

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3 May 2018

Xiao-Ping Zhong

7

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3 May 2018

language of work or name

English

0 references

publication date

8 October 2006

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3 May 2018

published in

Nature Immunology

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3 May 2018

volume

7

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3 May 2018

issue

11

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3 May 2018

page(s)

1174-1181

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3 May 2018

Back to central tolerance

cites work

1 reference

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Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion

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Anergic T-lymphocyte clones have altered inositol phosphate, calcium, and tyrosine kinase signaling pathways

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Transactivation by AP-1 is a molecular target of T cell clonal anergy

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Blocked Signal Transduction to the ERK and JNK Protein Kinases in Anergic CD4+ T Cells

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Regulation of T lymphocyte metabolism

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CD28 costimulatory signal induces protein arginine methylation in T cells.

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CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites

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Molecular events in the induction of a nonresponsive state in interleukin 2-producing helper T-lymphocyte clones

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Transcriptional mechanisms underlying lymphocyte tolerance.

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JNK is involved in signal integration during costimulation of T lymphocytes.

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IkappaB kinases serve as a target of CD28 signaling

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Expression of NFAT-family proteins in normal human T cells

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Differential activation of transcription factors induced by Ca2+ response amplitude and duration

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RasGRP is essential for mouse thymocyte differentiation and TCR signaling

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Enhanced T cell responses due to diacylglycerol kinase zeta deficiency

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7 January 2021

Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta

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7 January 2021

Phosphatidylinositol hydrolysis in freshly isolated human T lymphocytes

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7 January 2021

B-cell antigen receptor activates transcription factors NFAT (nuclear factor of activated T-cells) and NF-kappaB (nuclear factor kappaB) via a mechanism that involves diacylglycerol

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7 January 2021

In vivo induction of anergy in peripheral V beta 8+ T cells by staphylococcal enterotoxin B.

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7 January 2021

Selective anergy of V beta 8+,CD4+ T cells in Staphylococcus enterotoxin B-primed mice

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Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes

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7 January 2021

Expression of a catalytically inactive form of diacylglycerol kinase alpha induces sustained signaling through RasGRP.

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7 January 2021

The role of diacylglycerol kinase activation and phosphatidate accumulation in interleukin-2-dependent lymphocyte proliferation.

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7 January 2021

Protein and lipid kinase activation cascades in interleukin-2 receptor signalling.

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7 January 2021

Phosphatidic acid generation through interleukin 2 (IL-2)-induced alpha-diacylglycerol kinase activation is an essential step in IL-2-mediated lymphocyte proliferation

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7 January 2021

Interleukin-2 stimulates a late increase in phosphatidic acid production in the absence of phospholipase D activation.

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7 January 2021

The role of cell division in the induction of clonal anergy

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7 January 2021

Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions

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7 January 2021

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7 January 2021

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Diacylglycerol kinase zeta regulates phosphatidylinositol 4-phosphate 5-kinase Ialpha by a novel mechanism

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7 January 2021

Selective inhibition of phosphatidylinositol 3-kinase by phosphatidic acid and related lipids

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7 January 2021

T cell activation in vivo targets diacylglycerol kinase alpha to the membrane: a novel mechanism for Ras attenuation

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7 January 2021

Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase alpha by D-alpha-tocopherol.

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7 January 2021

Selective translocation of diacylglycerol kinase zeta in hippocampal neurons under transient forebrain ischemia

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7 January 2021

Nuclei contain two differentially regulated pools of diacylglycerol

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7 January 2021

Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta

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7 January 2021

Diacylglycerol Kinase-ζ Localization in Skeletal Muscle Is Regulated by Phosphorylation and Interaction with Syntrophins

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7 January 2021

Regulation of diacylglycerol kinase alpha by phosphoinositide 3-kinase lipid products

1 reference

7 January 2021

Protein kinase C alpha phosphorylates and negatively regulates diacylglycerol kinase zeta

1 reference

7 January 2021

Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin

1 reference

7 January 2021

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