(Q35096668)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

review article

1 reference

title

Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Frédérique Michel

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

Oreste Acuto

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Setsuko Mise-Omata

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

publication date

1 April 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

published in

Immunological Reviews

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

192

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

21-31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells

2 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Direct observation of ligand recognition by T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

21 January 2018

The B7-CD28 superfamily

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

CD28 costimulation: a source of Vav-1 for TCR signaling with the help of SLP-76?

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Quantitative analysis of leukocyte membrane antigen expression: normal adult values.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

The immunological synapse and CD28-CD80 interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

The interaction properties of costimulatory molecules revisited.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Ligand recognition by alpha beta T cell receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Conformational regulation of integrin structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

CD2 sets quantitative thresholds in T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

CD28/B7 system of T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

CD28 affects the earliest signaling events generated by TCR engagement

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Dependence of T cell antigen recognition on the dimensions of an accessory receptor-ligand complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Mechanisms contributing to the activity of integrins on leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Positive and negative regulation of T-cell activation by adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

GRID: a novel Grb-2-related adapter protein that interacts with the activated T cell costimulatory receptor CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Role of Tec kinase in nuclear factor of activated T cells signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Regulation of Lck activity by CD4 and CD28 in the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Signal-dependent membrane targeting by pleckstrin homology (PH) domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

A point mutation in CD28 distinguishes proliferative signals from survival signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

The role of Tec protein-tyrosine kinase in T cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

New insights into the regulation and functions of Tec family tyrosine kinases in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

VAV proteins as signal integrators for multi-subunit immune-recognition receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Two distinct regions of the CD28 intracytoplasmic domain are involved in the tyrosine phosphorylation of Vav and GTPase activating protein-associated p62 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Vav1 regulates phospholipase cgamma activation and calcium responses in mast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

The duration of antigenic stimulation determines the fate of naive and effector T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Three-dimensional segregation of supramolecular activation clusters in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

The immunological synapse: a molecular machine controlling T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Differential clustering of CD4 and CD3zeta during T cell recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Membrane rafts and signaling by the multichain immune recognition receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

CD28 co-stimulates TCR/CD3-induced phosphoinositide turnover in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Receptor avidity and costimulation specify the intracellular Ca2+ signaling pattern in CD4(+)CD8(+) thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Antigen receptor engagement delivers a stop signal to migrating T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

T cell receptor signaling precedes immunological synapse formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Formation and function of the immunological synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Protein kinase C-theta;: signaling from the center of the T-cell synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Homeostatic control of lymphocyte survival: potential origins and implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Quantitation of lysozyme peptides bound to class II MHC molecules indicates very large differences in levels of presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Coordinate regulation of T cell activation by CD2 and CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Live-cell dynamics and the role of costimulation in immunological synapse formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

A receptor/cytoskeletal movement triggered by costimulation during T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

T lymphocyte costimulation mediated by reorganization of membrane microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Transport of peptide-MHC class II complexes in developing dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

Cutting edge: B7/CD28 interactions regulate cell cycle progression independent of the strength of TCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

T cell activation determined by T cell receptor number and tunable thresholds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

Duration of TCR stimulation determines costimulatory requirement of T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

Interaction between human CD2 and CD58 involves the major beta sheet surface of each of their respective adhesion domains

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

Characteristics of antigen-independent and antigen-dependent interaction of dendritic cells with CD4+ T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

CD28 as a molecular amplifier extending TCR ligation and signaling capabilities.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

Absence of B7-dependent responses in CD28-deficient mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

Differential T cell costimulatory requirements in CD28-deficient mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

Upstream-downstream: CD28 cosignaling pathways and T cell function

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

Protein kinase C(theta) in T cell activation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

The Actin Cytoskeleton and Lymphocyte Activation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

CD28 Signaling via VAV/SLP-76 Adaptors

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00034.X

7 January 2021

10.1034/J.1600-065X.2003.00034.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12670392%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference