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CD28 Signaling via VAV/SLP-76 Adaptors
scientific article published on 01 December 2001
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scholarly article
1 reference
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Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
title
CD28 signaling via VAV/SLP-76 adaptors: regulation of cytokine transcription independent of TCR ligation
(English)
1 reference
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Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
author
Stefan M. Pfister
series ordinal
2
1 reference
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Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
author name string
M Raab
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
C E Rudd
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
language of work or name
English
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publication date
1 December 2001
1 reference
stated in
Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
published in
Immunity
1 reference
stated in
Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
volume
15
1 reference
stated in
Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
page(s)
921-933
1 reference
stated in
Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
issue
6
1 reference
stated in
Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
cites work
Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
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7 January 2021
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Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation
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7 January 2021
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New perspectives of CD28-B7-mediated T cell costimulation
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7 January 2021
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Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.
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7 January 2021
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Regulatory and signaling properties of the Vav family
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reference URL
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7 January 2021
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Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
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CD28 co-stimulatory regimes differ in their dependence on phosphatidylinositol 3-kinase: common co-signals induced by CD80 and CD86
1 reference
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reference URL
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7 January 2021
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Cbl-b regulates the CD28 dependence of T-cell activation.
1 reference
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7 January 2021
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Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development.
1 reference
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7 January 2021
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The protecton: the unit of humoral immunity selected by evolution
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7 January 2021
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Cloning of a novel T-cell protein FYB that binds FYN and SH2-domain-containing leukocyte protein 76 and modulates interleukin 2 production
1 reference
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7 January 2021
based on heuristic
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SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity
1 reference
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Crossref
reference URL
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7 January 2021
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Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor
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7 January 2021
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Phosphoinositide binding domains: embracing 3-phosphate
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7 January 2021
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Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
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Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction
1 reference
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Crossref
reference URL
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7 January 2021
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Activation-dependent phosphorylation of the T-lymphocyte surface receptor CD28 and associated proteins
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The ups and downs of T cell costimulation
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The B7 and CD28 receptor families
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling
1 reference
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Crossref
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7 January 2021
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The origin and mechanism of the allograft reaction
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7 January 2021
based on heuristic
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The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
A point mutation in CD28 distinguishes proliferative signals from survival signals
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adaptor proteins in lymphocyte antigen-receptor signaling.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription factors of the NFAT family: regulation and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Upstream-downstream: CD28 cosignaling pathways and T cell function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adaptors and molecular scaffolds in immune cell signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adaptor proteins and T-cell antigen receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cell culture model for T lymphocyte clonal anergy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28-mediated induction of proliferation in resting T cells in vitro and in vivo without engagement of the T cell receptor: evidence for functionally distinct forms of CD28
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 affects the earliest signaling events generated by TCR engagement.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T lymphocyte costimulation mediated by reorganization of membrane microdomains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900248-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(01)00248-5
1 reference
stated in
Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
PubMed ID
11754814
1 reference
stated in
Europe PubMed Central
PubMed ID
11754814
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754814%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
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