(Q52575315)

3 May 2018

title

STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity. (English)

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3 May 2018

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2

Ogyi Park

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3 May 2018

author name string

Won-Il Jeong

series ordinal

1

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3 May 2018

Svetlana Radaeva

series ordinal

3

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3 May 2018

Bin Gao

series ordinal

4

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3 May 2018

language of work or name

English

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publication date

1 December 2006

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3 May 2018

published in

Hepatology

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3 May 2018

volume

44

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3 May 2018

issue

6

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3 May 2018

page(s)

1441-1451

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3 May 2018

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7 January 2021

Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets

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7 January 2021

Reversal of hepatic fibrosis -- fact or fantasy?

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7 January 2021

Mechanisms of liver fibrosis

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7 January 2021

Liver fibrosis: from the bench to clinical targets

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7 January 2021

Transforming growth factor beta and the liver

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7 January 2021

PDGF and signal transduction in hepatic stellate cells

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7 January 2021

Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats

1 reference

7 January 2021

Expression of platelet-derived growth factor in a model of acute liver injury

1 reference

7 January 2021

Effects of platelet-derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells

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7 January 2021

Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture

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7 January 2021

Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma

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7 January 2021

Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins

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7 January 2021

Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses

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7 January 2021

Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners

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7 January 2021

Interferon gamma decreases hepatic stellate cell activation and extracellular matrix deposition in rat liver fibrosis

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7 January 2021

Interferon alfa down-regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice

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7 January 2021

Improvement of liver fibrosis in chronic hepatitis C patients treated with natural interferon alpha

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7 January 2021

Treatment of chronic hepatitis C virus infection in patients with cirrhosis

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7 January 2021

Impact of pegylated interferon alfa-2b and ribavirin on liver fibrosis in patients with chronic hepatitis C.

1 reference

7 January 2021

Effect of peginterferon alfa-2a on liver histology in chronic hepatitis C: a meta-analysis of individual patient data

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7 January 2021

Effect of interferon-gamma on hepatic fibrosis in chronic hepatitis B virus infection: a randomized controlled study

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7 January 2021

Interferon gamma-1b for the treatment of fibrosis in chronic hepatitis C infection

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7 January 2021

Antifibrotic agents for liver disease

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7 January 2021

Inhibition of rat hepatic lipocyte activation in culture by interferon-gamma

1 reference

7 January 2021

Interferon alfa and gamma inhibit proliferation and collagen synthesis of human Ito cells in culture

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7 January 2021

TGF-beta/Smad signaling in the injured liver

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7 January 2021

Signaling pathways activated by interferons

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7 January 2021

Host factors and failure of interferon-alpha treatment in hepatitis C virus

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7 January 2021

Acetylcholine promotes the proliferation and collagen gene expression of myofibroblastic hepatic stellate cells

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7 January 2021

STAT1 contributes to dsRNA inhibition of liver regeneration after partial hepatectomy in mice.

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7 January 2021

Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery

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7 January 2021

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

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7 January 2021

IRF-1 as a negative regulator of cell proliferation

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/CBP transcriptional coactivators

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7 January 2021

Y-box protein-1 is the crucial mediator of antifibrotic interferon-gamma effects

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7 January 2021

Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC.

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7 January 2021

Activation-induced cell death of hepatic stellate cells by the innate immune system

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7 January 2021

Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing

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7 January 2021

Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis.

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7 January 2021

Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C

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7 January 2021

Hepatitis C virus inhibits interferon signaling through up-regulation of protein phosphatase 2A.

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7 January 2021

Gene expression patterns that correlate with hepatitis C and early progression to fibrosis in liver transplant recipients

1 reference

7 January 2021

Altered expression and activation of signal transducers and activators of transcription (STATs) in hepatitis C virus infection: in vivo and in vitro studies

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7 January 2021

Identifiers

DOI

10.1002/HEP.21419

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3 May 2018

PubMed ID

17133483

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3 May 2018