(Q52595136)

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A Novel Mechanism of Mesenchymal Stromal Cell-Mediated Protection against Sepsis: Restricting Inflammasome Activation in Macrophages by Increasing Mitophagy and Decreasing Mitochondrial ROS.

scientific article published on 13 February 2018

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

A Novel Mechanism of Mesenchymal Stromal Cell-Mediated Protection against Sepsis: Restricting Inflammasome Activation in Macrophages by Increasing Mitophagy and Decreasing Mitochondrial ROS (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

inflammasome complex

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

6

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

10

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Europe PubMed Central

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22 March 2020

11

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

author name string

Shuang Li

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Wensi Fan

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Ran Zhang

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Miaomiao Fan

8

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Yuesheng Huang

9

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

publication date

13 February 2018

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Oxidative medicine and cellular longevity

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

2018

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

3537609

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

copyright license

Creative Commons Attribution 4.0 International

1 January 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Cardiac Function and Dysfunction in Sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Triggering of Parkin Mitochondrial Translocation in Mitophagy: Implications for Liver Diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Cardiac dysfunction and circulating cardiac markers during sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Mitochondrial dynamics, mitophagy and cardiovascular disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Mesenchymal stem cells: mechanisms of potential therapeutic benefit in ARDS and sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Gene silencing of non-obese diabetic receptor family (NLRP3) protects against the sepsis-induced hyper-bile acidaemia in a rat model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Myocardial protective effect of extracellular superoxide dismutase gene modified bone marrow mesenchymal stromal cells on infarcted mice hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Complete activation of autophagic process attenuates liver injury and improves survival in septic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Immunotherapy for the Adjunctive Treatment of Sepsis: From Immunosuppression to Immunostimulation. Time for a Paradigm Change?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Enhancing autophagy with activated protein C and rapamycin protects against sepsis-induced acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Impact of apoptotic adipose-derived mesenchymal stem cells on attenuating organ damage and reducing mortality in rat sepsis syndrome induced by cecal puncture and ligation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Critical role for calcium mobilization in activation of the NLRP3 inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Sepsis, systemic inflammatory response, and multiple organ dysfunction: the mystery continues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Inflammasomes in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Advances in mesenchymal stem cell research in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Mesenchymal stem cells and acute lung injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

A role for mitochondria in NLRP3 inflammasome activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Bone marrow mesenchymal stromal cells attenuate organ injury induced by LPS and burn

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Immunodesign of experimental sepsis by cecal ligation and puncture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Harmful molecular mechanisms in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Selective degradation of mitochondria by mitophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

22 May 2018

Isolation, Culture, and Polarization of Murine Bone Marrow-Derived and Peritoneal Macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

13 August 2018

Additional benefit of combined therapy with melatonin and apoptotic adipose-derived mesenchymal stem cell against sepsis-induced kidney injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

13 August 2018

Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

13 August 2018

Hospital Deaths in Patients With Sepsis From 2 Independent Cohorts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831900

30 November 2018

Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/29636842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesenchymal stem cells attenuate myocardial functional depression and reduce systemic and myocardial inflammation during endotoxemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29636842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29636842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete induction of autophagy is essential for cardioprotection in sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29636842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous infusion of mesenchymal stem cells is associated with improved myocardial function during endotoxemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29636842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29636842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melatonin treatment improves adipose-derived mesenchymal stem cell therapy for acute lung ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/29636842

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1155/2018/3537609

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29636842%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

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