(Q52609569)

English

Wnt/β-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects.

scientific article published in June 2011

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21452227%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Wnt/β-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21452227%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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27 January 2020

3

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Europe PubMed Central

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27 January 2020

author name string

Vassiliki Fotaki

1

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27 January 2020

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1 June 2011

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27 January 2020

The Journal of Comparative Neurology

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27 January 2020

519

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27 January 2020

9

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27 January 2020

1640-1657

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27 January 2020

Wnt canonical pathway restricts graded Shh/Gli patterning activity through the regulation of Gli3 expression.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Mouse GLI3 regulates Fgf8 expression and apoptosis in the developing neural tube, face, and limb bud

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Transgenic Wnt/TCF pathway reporters: all you need is Lef?

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Regulation of cerebral cortical size by control of cell cycle exit in neural precursors

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Increased neuronal production, enlarged forebrains and cytoarchitectural distortions in beta-catenin overexpressing transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

TCF-4 binds beta-catenin and is expressed in distinct regions of the embryonic brain and limbs

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Integration of telencephalic Wnt and hedgehog signaling center activities by Foxg1.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Wnt-3A/beta-catenin signaling induces transcription from the LEF-1 promoter

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Extra-toes (Xt) homozygous mutant mice demonstrate a role for the Gli-3 gene in the development of the forebrain

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Beta-catenin-mediated Wnt signaling regulates neurogenesis in the ventral telencephalon

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Specification of dorsal telencephalic character by sequential Wnt and FGF signaling

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

FGF signalling generates ventral telencephalic cells independently of SHH.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Vax1, a novel homeobox-containing gene, directs development of the basal forebrain and visual system

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

The genetics of early telencephalon patterning: some assembly required

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

A disrupted balance between Bmp/Wnt and Fgf signaling underlies the ventralization of the Gli3 mutant telencephalon.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Expression pattern of a murine homeobox gene, Dbx, displays extreme spatial restriction in embryonic forebrain and spinal cord

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Role of beta-catenin in the developing cortical and hippocampal neuroepithelium.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Lhx2 selector activity specifies cortical identity and suppresses hippocampal organizer fate.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Expression of Dbx1, Neurogenin 2, Semaphorin 5A, Cadherin 8, and Emx1 distinguish ventral and lateral pallial histogenetic divisions in the developing mouse claustroamygdaloid complex

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Wnt signals are targets and mediators of Gli function.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

A mutually stimulating loop involving emx2 and canonical wnt signalling specifically promotes expansion of occipital cortex and hippocampus.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Coordinate regulation and synergistic actions of BMP4, SHH and FGF8 in the rostral prosencephalon regulate morphogenesis of the telencephalic and optic vesicles

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

FGF8 signaling patterns the telencephalic midline by regulating putative key factors of midline development.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Patterning the dorsal telencephalon: a role for sonic hedgehog?

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Mouse Wnt8B is expressed in the developing forebrain and maps to chromosome 19.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Regionalization of the prosencephalic neural plate.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Expression of murine Lhx5 suggests a role in specifying the forebrain

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Embryonic signaling centers expressing BMP, WNT and FGF proteins interact to pattern the cerebral cortex.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Mechanisms underlying the specification, positional regulation, and function of the cortical hem.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Gli3 is required for the specification and differentiation of preplate neurons

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J)

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Inhibitory Gli3 activity negatively regulates Wnt/beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Heads or tails: Wnts and anterior-posterior patterning

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Expression and splice variant analysis of the zebrafish tcf4 transcription factor.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Analysis of early ventral telencephalic defects in mice lacking functional Gli3 protein

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Loss of Gli3 enhances the viability of embryonic telencephalic cells in vitro.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Neuronal production and precursor proliferation defects in the neocortex of mice with loss of function in the canonical Wnt signaling pathway

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Deletion of GLI3 supports the homology of the human Greig cephalopolysyndactyly syndrome (GCPS) and the mouse mutant extra toes (Xt)

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

21 January 2018

Sonic hedgehog induces the differentiation of ventral forebrain neurons: A common signal for ventral patterning within the neural tube

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

7 January 2021

based on heuristic

inferred from DOI database lookup

Pax-6 regulates expression of SFRP-2 and Wnt-7b in the developing CNS.

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

7 January 2021

based on heuristic

inferred from DOI database lookup

High-resolution mapping of the Gli3 mutation extra-toes reveals a 51.5-kb deletion

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

7 January 2021

based on heuristic

inferred from DOI database lookup

Gli3 is required autonomously for dorsal telencephalic cells to adopt appropriate fates during embryonic forebrain development

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

7 January 2021

based on heuristic

inferred from DOI database lookup

Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT).

1 reference

https://api.crossref.org/works/10.1002%2FCNE.22592

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/CNE.22592

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21452227%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21452227%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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