(Q52652196)

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Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA.

scientific article published on 16 March 2018

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scholarly article

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Europe PubMed Central

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20 March 2020

Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA (English)

1 reference

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20 March 2020

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20 March 2020

2

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20 March 2020

17

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20 March 2020

author name string

Karen Howarth

3

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20 March 2020

Mikidache Madi

4

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20 March 2020

Bradley Durham

5

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20 March 2020

Sarah Smalley

6

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20 March 2020

John Calaway

7

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20 March 2020

Shannon Blais

8

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20 March 2020

Greg Jones

9

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20 March 2020

James Clark

10

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20 March 2020

Peter Dimitrov

11

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20 March 2020

Michelle Pugh

12

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20 March 2020

Samuel Woodhouse

13

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20 March 2020

Michael Epstein

14

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20 March 2020

Ana Fernandez-Gonzalez

15

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20 March 2020

Alexandra S Whale

16

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20 March 2020

Carole A Foy

18

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20 March 2020

Gerwyn M Jones

19

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20 March 2020

Hadas Raveh-Amit

20

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20 March 2020

Karin Schmitt

21

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20 March 2020

Alison Devonshire

22

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20 March 2020

Emma Green

23

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20 March 2020

Tim Forshew

24

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20 March 2020

Vincent Plagnol

25

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20 March 2020

Nitzan Rosenfeld

26

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20 March 2020

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publication date

16 March 2018

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20 March 2020

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20 March 2020

13

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20 March 2020

3

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20 March 2020

e0194630

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20 March 2020

copyright license

Creative Commons Attribution 4.0 International

16 March 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Characterization of background noise in capture-based targeted sequencing data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Liquid biopsies come of age: towards implementation of circulating tumour DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Osimertinib benefit in EGFR-mutant NSCLC patients with T790M-mutation detected by circulating tumour DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Reproducibility of Digital PCR Assays for Circulating Tumor DNA Analysis in Advanced Breast Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Quantitation of next generation sequencing library preparation protocol efficiencies using droplet digital PCR assays - a systematic comparison of DNA library preparation kits for Illumina sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

The Ensembl Variant Effect Predictor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Detection of Rare Drug Resistance Mutations by Digital PCR in a Human Influenza A Virus Model System and Clinical Samples.

1 reference

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22 May 2018

Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA

1 reference

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22 May 2018

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Towards standardisation of cell-free DNA measurement in plasma: controls for extraction efficiency, fragment size bias and quantification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Detection of circulating tumor DNA in early- and late-stage human malignancies

1 reference

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22 May 2018

Safety and efficacy of vemurafenib in BRAF(V600E) and BRAF(V600K) mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study

1 reference

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22 May 2018

Noninvasive detection of response and resistance in EGFR-mutant lung cancer using quantitative next-generation genotyping of cell-free plasma DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Analysis of circulating tumor DNA to monitor metastatic breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Discovery and characterization of artifactual mutations in deep coverage targeted capture sequencing data due to oxidative DNA damage during sample preparation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

1 reference

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22 May 2018

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5856404

22 May 2018

Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

1 reference

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22 May 2018

Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma

1 reference

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22 May 2018

Circulating mutant DNA to assess tumor dynamics

1 reference

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22 May 2018

About the possible origin and mechanism of circulating DNA apoptosis and active DNA release

1 reference

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22 May 2018

1 reference

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22 May 2018

Identification of p53 gene mutations in bladder cancers and urine samples

1 reference

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22 May 2018

Tracking evolution of aromatase inhibitor resistance with circulating tumour DNA analysis in metastatic breast cancer.

1 reference

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13 August 2018

Direct detection of early-stage cancers using circulating tumor DNA.

1 reference

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13 August 2018

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

1 reference

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13 August 2018

Osimertinib or Platinum-Pemetrexed in EGFR T790M-Positive Lung Cancer.

1 reference

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13 August 2018

Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer.

1 reference

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13 August 2018

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1 reference

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13 August 2018

Identifiers

10.1371/JOURNAL.PONE.0194630

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29547634%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29547634%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29547634%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

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