(Q28385712)

21

Henrik Grönberg

0 references

Steven A McCarroll

Steven A McCarroll

23

0 references

Johan Lindberg

Johan Lindberg

4

0 references

Samuel F Bakhoum

Samuel F Bakhoum

6

0 references

Jennifer L. Moran

Jennifer L Moran

17

0 references

Samuel A Rose

Samuel A Rose

5

0 references

Christina M. Hultman

22

Christina M Hultman

0 references

Mikael Landén

13

Mikael Landén

0 references

Stacey Gabriel

16

Stacey B Gabriel

0 references

Patrick F. Sullivan

19

Patrick F Sullivan

0 references

Pamela Sklar

20

Pamela Sklar

0 references

Benjamin M. Neale

9

Benjamin M Neale

0 references

author name string

Giulio Genovese

1

0 references

Anna K Kähler

2

0 references

Robert E Handsaker

3

0 references

Kimberly Chambert

7

0 references

Eran Mick

8

0 references

Menachem Fromer

10

0 references

Shaun M Purcell

11

0 references

Oscar Svantesson

12

0 references

Martin Höglund

14

0 references

Sören Lehmann

The New England Journal of Medicine

15

0 references

language of work or name

English

0 references

publication date

25 December 2014

0 references

published in

0 references

volume

371

0 references

page(s)

2477-87

0 references

issue

26

0 references

cites work

Parental somatic mosaicism is underrecognized and influences recurrence risk of genomic disorders

1 reference

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The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers

20 March 2017

1 reference

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Discovery and saturation analysis of cancer genes across 21 tumour types

20 March 2017

1 reference

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Genome-wide association analysis identifies 13 new risk loci for schizophrenia

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Confirmation of the reported association of clonal chromosomal mosaicism with an increased risk of incident hematologic cancer

20 March 2017

1 reference

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Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Detectable clonal mosaicism and its relationship to aging and cancer

20 March 2017

1 reference

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Detectable clonal mosaicism from birth to old age and its relationship to cancer

20 March 2017

1 reference

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Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts

20 March 2017

1 reference

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DNMT3A Mutations in Acute Myeloid Leukemia

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Stem cells, cancer, and cancer stem cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

The clonal evolution of tumor cell populations

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

20 March 2017

1 reference

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Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

7 April 2017

1 reference

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Mutation in TET2 in myeloid cancers

7 April 2017

1 reference

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A gain-of-function mutation of JAK2 in myeloproliferative disorders

7 April 2017

1 reference

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Acquired initiating mutations in early hematopoietic cells of CLL patients

7 April 2017

1 reference

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Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

A polygenic burden of rare disruptive mutations in schizophrenia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Dynamics of ASXL1 mutation and other associated genetic alterations during disease progression in patients with primary myelodysplastic syndrome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Mutational landscape of AML with normal cytogenetics: biological and clinical implications.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

The role of mutations in epigenetic regulators in myeloid malignancies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Dnmt3a is essential for hematopoietic stem cell differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

PPM1D430, a novel alternative splicing variant of the human PPM1D, can dephosphorylate p53 and exhibits specific tissue expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

On the origin of leukemic species.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

PPM1D mutations in circulating white blood cells and the risk for ovarian cancer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

The role of different genetic subtypes of CEBPA mutated AML.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4290021

Persistence of leukaemic ancestors

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25426838

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

MDS is a stem cell disorder after all

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25426838