(Q33813999)

29 July 2017

title

Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas (English)

1 reference

29 July 2017

8

Siân Jones

0 references

Zachary J Reitman

object named as

Zachary J Reitman

23

0 references

Henry Seth Friedman

19

object named as

Henry S Friedman

1 reference

29 July 2017

24

Darell D Bigner

1 reference

29 July 2017

20

Allan H Friedman

1 reference

29 July 2017

21

Roger E McLendon

1 reference

29 July 2017

12

Patrick J Killela

1 reference

29 July 2017

11

Huishan Zhu

1 reference

29 July 2017

Liwei Zhang

1

1 reference

29 July 2017

Lee H Chen

2

1 reference

29 July 2017

Hong Wan

3

1 reference

29 July 2017

Rui Yang

4

1 reference

29 July 2017

Zhaohui Wang

5

1 reference

29 July 2017

Jie Feng

6

1 reference

29 July 2017

Shaohua Yang

7

1 reference

29 July 2017

Sizhen Wang

9

1 reference

29 July 2017

Weixin Zhou

10

1 reference

29 July 2017

Junting Zhang

13

1 reference

29 July 2017

Zhen Wu

14

1 reference

29 July 2017

Guilin Li

15

1 reference

29 July 2017

Shuyu Hao

16

1 reference

29 July 2017

Yu Wang

17

1 reference

29 July 2017

Joseph B Webb

18

1 reference

29 July 2017

Yiping He

22

1 reference

29 July 2017

Hai Yan

25

1 reference

29 July 2017

language of work or name

English

0 references

publication date

1 June 2014

1 reference

29 July 2017

1 reference

29 July 2017

volume

46

1 reference

29 July 2017

issue

7

1 reference

29 July 2017

page(s)

726-730

1 reference

Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction.

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Genetic variants and mutations of PPM1D control the response to DNA damage.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

IDH mutation impairs histone demethylation and results in a block to cell differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

A small molecule inhibitor of p53-inducible protein phosphatase PPM1D.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Dephosphorylation of γ-H2AX by WIP1: an important homeostatic regulatory event in DNA repair and cell cycle control

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

A method and server for predicting damaging missense mutations

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

IDH1 and IDH2 mutations in gliomas

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

An integrated genomic analysis of human glioblastoma multiforme

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4073211

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

4 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.2995

Classification of microarrays to nearest centroids.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.2995

The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24880341

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.2995

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference