(Q27559610)

21

0 references

Cyriac Kandoth

Cyriac Kandoth

7

0 references

Sean D. McGrath

Sean D McGrath

24

0 references

Timothy A. Graubert

Timothy A Graubert

45

0 references

Joshua F. McMichael

22

Joshua F McMichael

0 references

Richard K. Wilson

48

Richard K Wilson

0 references

Kim Delehaunty

23

Kim D Delehaunty

0 references

Lucinda Fulton

25

Lucinda A Fulton

0 references

Michael D McLellan

4

Michael D McLellan

0 references

Dan Koboldt

16

Daniel C Koboldt

0 references

Timothy Ley

1

Timothy J Ley

0 references

Michael H Tomasson

43

Michael H Tomasson

0 references

Heather Schmidt

17

Heather Schmidt

0 references

Joelle Kalicki

36

Joelle Kalicki

0 references

Todd Wylie

34

Todd Wylie

0 references

David Dooling

15

David J Dooling

0 references

Tammi L Vickery

27

Tammi L Vickery

0 references

Jacqueline E Payton

8

Jacqueline E Payton

0 references

Jack Baty

9

Jack Baty

0 references

Rakesh Nagarajan

41

Rakesh Nagarajan

0 references

John DiPersio

46

John F DiPersio

0 references

Qunyuan Zhang

18

Qunyuan Zhang

0 references

Nobish Varghese

40

Nobish Varghese

0 references

Jasreet Hundal

28

Jasreet Hundal

0 references

Gary W Swift

31

Gary W Swift

0 references

author name string

Li Ding

2

0 references

Matthew J Walter

3

0 references

Tamara Lamprecht

5

0 references

David E Larson

6

0 references

John Welch

10

0 references

Christopher C Harris

11

0 references

Cheryl F Lichti

12

0 references

R Reid Townsend

13

0 references

Robert S Fulton

14

0 references

John R Osborne

19

0 references

Ling Lin

20

0 references

Michelle O'Laughlin

21

0 references

Vincent J Magrini

26

0 references

Lisa L Cook

29

0 references

Joshua J Conyers

30

0 references

Jerry P Reed

32

0 references

Patricia A Alldredge

33

0 references

Jason Walker

35

0 references

Mark A Watson

37

0 references

Sharon Heath

38

0 references

William D Shannon

39

0 references

Peter Westervelt

42

0 references

Daniel C Link

The New England Journal of Medicine

44

0 references

language of work or name

English

0 references

publication date

16 December 2010

0 references

published in

0 references

volume

363

0 references

page(s)

2424-33

0 references

issue

25

0 references

on focus list of Wikimedia project

ScienceSource

0 references

cites work

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Recurring mutations found by sequencing an acute myeloid leukemia genome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Prevalence and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML).

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Myc represses transcription through recruitment of DNA methyltransferase corepressor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

The cancer epigenome--components and functional correlates

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

20 March 2017

Epigenetics in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

7 April 2017

Epigenetics in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

DNA hypomethylation in cancer cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Array-based genomic resequencing of human leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Rethinking how DNA methylation patterns are maintained

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

DNA methyltransferase-3a interacts with p53 and represses p53-mediated gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

DNMT3B mutations and DNA methylation defect define two types of ICF syndrome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Prognostic impact of isocitrate dehydrogenase enzyme isoforms 1 and 2 mutations in acute myeloid leukemia: a study by the Acute Leukemia French Association group

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

DNA methyltransferases control telomere length and telomere recombination in mammalian cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201818

27 November 2018

Identifiers

DOI

10.1056/NEJMOA1005143

1 reference

11647

11647

1 reference

1 reference

1 reference