(Q52689481)

5 May 2018

title

Impact of reduced insulin-like growth factor-1/insulin signaling on aging in mammals: novel findings. (English)

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5 May 2018

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1

Andrzej Bartke

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5 May 2018

publication date

11 March 2008

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5 May 2018

published in

Aging Cell

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5 May 2018

volume

7

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5 May 2018

page(s)

285-290

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5 May 2018

issue

3

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5 May 2018

Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Gene expression profile of long-lived Ames dwarf mice and Little mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Alterations in xenobiotic metabolism in the long-lived Little mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Genetics of aging in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Glucose regulation and oxidative stress in healthy centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Prolonged longevity of hypopituitary dwarf mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Consequences of growth hormone (GH) overexpression and GH resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Effects of Soy-derived diets on plasma and liver lipids, glucose tolerance, and longevity in normal, long-lived and short-lived mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Comparing adiposity profiles in three mouse models with altered GH signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Extended longevity in mice lacking the insulin receptor in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Dwarf mice and the ageing process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Role of brain insulin receptor in control of body weight and reproduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

The little mutation suppresses DEN-induced hepatocarcinogenesis in mice and abrogates genetic and hormonal modulation of susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Assessment of growth parameters and life span of GHR/BP gene-disrupted mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

The role of the insulin-like growth factors in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Reduced growth of human sarcoma xenografts in hosts homozygous for the lit mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-1 and IRS-2 in liver of Ames dwarf mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Insulin-like growth factor-I receptors and estrogen receptors interact in the promotion of neuronal survival and neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Reduced insulin/IGF-1 signalling and human longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Body composition of prolactin-, growth hormone, and thyrotropin-deficient Ames dwarf mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Low body temperature in long-lived Ames dwarf mice at rest and during stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

The plasticity of aging: insights from long-lived mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Suppression of aging in mice by the hormone Klotho

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Lack of evidence of premature atherosclerosis in untreated severe isolated growth hormone (GH) deficiency due to a GH-releasing hormone receptor mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Big mice die young: early life body weight predicts longevity in genetically heterogeneous mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Central and opposing effects of IGF-I and IGF-binding protein-3 on systemic insulin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Prolactin and growth hormone regulate adiponectin secretion and receptor expression in adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Comparative longevity of pet dogs and humans: implications for gerontology research

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Targeted neuronal gene expression and longevity in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Transgenic overexpression of pregnancy-associated plasma protein-A increases the somatic growth and skeletal muscle mass in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Long-lived Ames dwarf mouse exhibits increased antioxidant defense in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Endocrine regulation of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Is height related to longevity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Regulation of carbohydrate metabolism by the farnesoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Functionally significant insulin-like growth factor I receptor mutations in centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Brain IRS2 signaling coordinates life span and nutrient homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Growth hormone secretagogues in critical illness

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

Regulation of C. elegans life-span by insulinlike signaling in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2008.00387.X

10.1111/J.1474-9726.2008.00387.X

21 January 2018

Identifiers

DOI

1 reference

5 May 2018

PubMed ID

18346217

1 reference

5 May 2018