(Q52699899)

English

Genentech obtains proof of concept for hedgehog inhibition.

scientific article published in November 2009

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Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 May 2018

http://europepmc.org/abstract/MED/19898437

Genentech obtains proof of concept for hedgehog inhibition. (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 May 2018

http://europepmc.org/abstract/MED/19898437

author name string

Cormac Sheridan

1

1 reference

Europe PubMed Central

PubMed publication ID

6 May 2018

http://europepmc.org/abstract/MED/19898437

publication date

1 November 2009

1 reference

Europe PubMed Central

PubMed publication ID

6 May 2018

http://europepmc.org/abstract/MED/19898437

Nature Biotechnology

1 reference

Europe PubMed Central

PubMed publication ID

6 May 2018

http://europepmc.org/abstract/MED/19898437

27

1 reference

Europe PubMed Central

PubMed publication ID

6 May 2018

http://europepmc.org/abstract/MED/19898437

11

1 reference

Europe PubMed Central

PubMed publication ID

6 May 2018

http://europepmc.org/abstract/MED/19898437

968-969

1 reference

Europe PubMed Central

PubMed publication ID

6 May 2018

http://europepmc.org/abstract/MED/19898437

https://scigraph.springernature.com/pub.10.1038/nbt1109-968

0 references

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A small molecule that binds Hedgehog and blocks its signaling in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hedgehog signaling is dispensable for adult hematopoietic stem cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19898437

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NBT1109-968

1 reference

Europe PubMed Central

PubMed publication ID

6 May 2018

http://europepmc.org/abstract/MED/19898437

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 May 2018

http://europepmc.org/abstract/MED/19898437

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