(Q52723729)

http://europepmc.org/abstract/PMC/6485619

2 July 2019

title

IκB Kinase α Is Required for Development and Progression of KRAS-Mutant Lung Adenocarcinoma. (English)

1 reference

http://europepmc.org/abstract/PMC/6485619

2 July 2019

author

Torsten Goldmann

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Georgios T. Stathopoulos

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Ioanna Giopanou

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Theodora Agalioti

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Vasileios Armenis

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Sebastian Marwitz

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Manolis Pasparakis

15

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8 June 2020

author name string

Malamati Vreka

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Ioannis Lilis

2

1 reference

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8 June 2020

Maria Papageorgopoulou

3

1 reference

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8 June 2020

Georgia A Giotopoulou

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Marina Lianou

5

1 reference

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8 June 2020

Nikolaos I Kanellakis

7

1 reference

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8 June 2020

Magda Spella

8

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8 June 2020

Fiona E Yull

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Timothy S Blackwell

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Antonia Marazioti

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

language of work or name

English

0 references

publication date

27 March 2018

1 reference

http://europepmc.org/abstract/PMC/6485619

2 July 2019

published in

Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

78

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

11

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8 June 2020

page(s)

2939-2951

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis

8 June 2020

cites work

1 reference

12 December 2020

Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

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12 December 2020

Increased expression of nuclear factor-kappaB in bronchial biopsies from smokers and patients with COPD.

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12 December 2020

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

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12 December 2020

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

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12 December 2020

Mouse reporter strain for noninvasive bioluminescent imaging of cells that have undergone Cre-mediated recombination.

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12 December 2020

Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras

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12 December 2020

Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium

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12 December 2020

Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

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12 December 2020

Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma

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12 December 2020

Structure-based design of 7-carbamate analogs of geldanamycin

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12 December 2020

IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy

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12 December 2020

A global double-fluorescent Cre reporter mouse

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12 December 2020

Epithelial NF-kappaB activation promotes urethane-induced lung carcinogenesis

1 reference

12 December 2020

Host nuclear factor-kappaB activation potentiates lung cancer metastasis

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12 December 2020

The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis

1 reference

12 December 2020

1 reference

12 December 2020

IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver

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12 December 2020

Randomized phase II trial of docetaxel plus cetuximab or docetaxel plus bortezomib in patients with advanced non-small-cell lung cancer and a performance status of 2: CALGB 30402.

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12 December 2020

Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma

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12 December 2020

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

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12 December 2020

Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation

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12 December 2020

An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure

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12 December 2020

17-DMAG targets the nuclear factor-kappaB family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition

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12 December 2020

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

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12 December 2020

FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR.

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12 December 2020

Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma

1 reference

12 December 2020

Neutralization of tumor necrosis factor bioactivity ameliorates urethane-induced pulmonary oncogenesis in mice

1 reference

12 December 2020

KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.

1 reference

12 December 2020

Opposing effects of bortezomib-induced nuclear factor-κB inhibition on chemical lung carcinogenesis

1 reference

12 December 2020

Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model

1 reference

12 December 2020

An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice.

1 reference

12 December 2020

Targeting NF-κB in mouse models of lung adenocarcinoma

1 reference

12 December 2020

Pulmonary autotaxin expression contributes to the pathogenesis of pulmonary fibrosis

1 reference

12 December 2020

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer

1 reference

12 December 2020

Dragging ras back in the ring

1 reference

12 December 2020

An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.

1 reference

12 December 2020

IKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity

1 reference

12 December 2020

Comprehensive molecular profiling of lung adenocarcinoma

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12 December 2020

The mutational landscapes of genetic and chemical models of Kras-driven lung cancer

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12 December 2020

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

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12 December 2020

Comprehensive Evaluation of Nuclear Factor-κΒ Expression Patterns in Non-Small Cell Lung Cancer.

1 reference

12 December 2020

The Global Burden of Cancer 2013

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12 December 2020

Downregulation of the TGFβ Pseudoreceptor BAMBI in Non-Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.

1 reference

12 December 2020

Neutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer

1 reference

12 December 2020

Tumor-derived osteopontin isoforms cooperate with TRP53 and CCL2 to promote lung metastasis

1 reference

12 December 2020

Mutant KRAS promotes malignant pleural effusion formation

1 reference

12 December 2020

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor.

1 reference

12 December 2020

10.1158/0008-5472.CAN-17-1944

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29588349%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

1 reference