(Q52826459)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25231866%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Statin treatment rescues FGFR3 skeletal dysplasia phenotypes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25231866%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

0 references

8

1 reference

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16 February 2020

Noriyuki Tsumaki

10

1 reference

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16 February 2020

author name string

Akihiro Yamashita

1

1 reference

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16 February 2020

Miho Morioka

2

1 reference

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16 February 2020

Hiromi Kishi

3

1 reference

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16 February 2020

Takeshi Kimura

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25231866%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Yasuhito Yahara

5

1 reference

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16 February 2020

Minoru Okada

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25231866%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Kaori Fujita

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25231866%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Shiro Ikegawa

9

1 reference

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16 February 2020

language of work or name

English

0 references

publication date

17 September 2014

1 reference

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16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25231866%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

513

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25231866%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

issue

7519

1 reference

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16 February 2020

page(s)

507-511

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describes a project that uses

16 February 2020

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https://scigraph.springernature.com/pub.10.1038/nature13775

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cites work

Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Nosology and classification of genetic skeletal disorders: 2010 revision.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Achondroplasia: pathogenesis and implications for future treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Systemic administration of C-type natriuretic peptide as a novel therapeutic strategy for skeletal dysplasias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

The transmembrane mutation G380R in fibroblast growth factor receptor 3 uncouples ligand-mediated receptor activation from down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

A more efficient method to generate integration-free human iPS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Directed differentiation of human embryonic stem cells toward chondrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCgamma-activated STAT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Sprouty 2 disturbs FGFR3 degradation in thanatophoric dysplasia type II: a severe form of human achondroplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

PTHrP rescues ATDC5 cells from apoptosis induced by FGF receptor 3 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Pravastatin suppresses matrix metalloproteinase expression and activity in human articular chondrocytes stimulated by interleukin-1β

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Stimulation of bone formation in vitro and in rodents by statins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Statins and the autonomic nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Statins, autophagy and cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Dangers of rosuvastatin identified before and after FDA approval

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Use of a new adhesive film for the preparation of multi-purpose fresh-frozen sections from hard tissues, whole-animals, insects and plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Birth of mice from vitrified/warmed 2-cell embryos transported at a cold temperature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Identification of small molecular compounds and fabrication of its aqueous solution by laser-ablation, expanding primordial cartilage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Primary culture and phenotyping of murine chondrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Generation of hyaline cartilaginous tissue from mouse adult dermal fibroblast culture by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13775

Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells

21 January 2018

1 reference

12 December 2020

Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3

1 reference

12 December 2020

Protective effect of atorvastatin in cultured osteoarthritic chondrocytes.

1 reference

12 December 2020

Fibroblast growth factor receptor 3 mutations promote apoptosis but do not alter chondrocyte proliferation in thanatophoric dysplasia

1 reference

12 December 2020

Postnatal soluble FGFR3 therapy rescues achondroplasia symptoms and restores bone growth in mice.

1 reference

12 December 2020

Intermittent PTH (1-34) injection rescues the retarded skeletal development and postnatal lethality of mice mimicking human achondroplasia and thanatophoric dysplasia

1 reference

12 December 2020

Telomere/Telomerase system: a new target of statins pleiotropic effect?

1 reference

12 December 2020