(Q52928127)

9 May 2018

review article

1 reference

title

Pathogenesis of hepatitis B virus infection. (English)

1 reference

9 May 2018

1 reference

1 reference

1

Thomas F Baumert

1 reference

9 May 2018

author name string

Robert Thimme

series ordinal

2

1 reference

9 May 2018

Fritz von Weizsäcker

series ordinal

3

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9 May 2018

language of work or name

English

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publication date

1 January 2007

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9 May 2018

World Journal of Gastroenterology

published in

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9 May 2018

volume

13

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9 May 2018

issue

1

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9 May 2018

page(s)

82-90

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9 May 2018

High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases

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22 May 2018

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22 May 2018

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22 May 2018

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Functional analysis of hepatitis B virus reactivating in hepatitis B surface antigen-negative individuals

22 May 2018

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Immunology of hepatitis B virus and hepatitis C virus infection

22 May 2018

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Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with hepatitis B virus infection

22 May 2018

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Comparison of adefovir and tenofovir in the treatment of lamivudine-resistant hepatitis B virus infection

22 May 2018

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Lamivudine for patients with chronic hepatitis B and advanced liver disease

22 May 2018

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Mechanism of viral persistence and resistance to nucleoside and nucleotide analogs in chronic hepatitis B virus infection

22 May 2018

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Basal core promoter and precore mutations in the hepatitis B virus genome enhance replication efficacy of Lamivudine-resistant mutants

22 May 2018

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Regulation of hepatitis B virus core promoter by transcription factors HNF1 and HNF4 and the viral X protein

22 May 2018

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Treatment of patients with chronic hepatitis B with adefovir dipivoxil

22 May 2018

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Clinical trial results and treatment resistance with lamivudine in hepatitis B.

22 May 2018

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Genomic analysis of the host response to hepatitis B virus infection

22 May 2018

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Hepatitis B virus infection--natural history and clinical consequences

22 May 2018

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Mutations of the surface protein of hepatitis B virus

22 May 2018

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An outbreak of fulminant hepatitis B in immunocompromised hemodialysis patients

22 May 2018

1 reference

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Deficiency in virion secretion and decreased stability of the hepatitis B virus immune escape mutant G145R

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

The hepatitis B virus polymerase mutation rtV173L is selected during lamivudine therapy and enhances viral replication in vitro.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Genome replication, virion secretion, and e antigen expression of naturally occurring hepatitis B virus core promoter mutants.

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Pro-apoptotic function of HBV X protein is mediated by interaction with c-FLIP and enhancement of death-inducing signal

22 May 2018

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Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B

22 May 2018

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CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection

22 May 2018

1 reference

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Cellular vacuolization and apoptosis induced by hepatitis B virus large surface protein

22 May 2018

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Virus-Specific CD8+ Lymphocytes Share the Same Effector-Memory Phenotype but Exhibit Functional Differences in Acute Hepatitis B and C

22 May 2018

1 reference

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Antiviral therapy for hepatitis B virus infections: new targets and technical challenges

22 May 2018

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Escaping high viral load exhaustion: CD8 cells with altered tetramer binding in chronic hepatitis B virus infection

22 May 2018

1 reference

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Degenerate immunogenicity of an HLA-A2-restricted hepatitis B virus nucleocapsid cytotoxic T-lymphocyte epitope that is also presented by HLA-B51.

22 May 2018

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Noncytolytic control of viral infections by the innate and adaptive immune response

22 May 2018

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Role of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection

22 May 2018

1 reference

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Hepatitis B virus replication: novel roles for virus-host interactions.

22 May 2018

1 reference

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Differential antigen-processing pathways of the hepatitis B virus e and core proteins

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Acute liver injury following infection with a cytopathic strain of duck hepatitis B virus

22 May 2018

1 reference

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Mechanism of suppression of hepatitis B virus precore RNA transcription by a frequent double mutation.

22 May 2018

1 reference

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Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Naturally occurring mutations define a novel function of the hepatitis B virus core promoter in core protein expression

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

A one-year trial of lamivudine for chronic hepatitis B. Asia Hepatitis Lamivudine Study Group.

22 May 2018

1 reference

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Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Lamivudine Clinical Investigation Group

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

A preS mutation isolated from a patient with chronic hepatitis B infection leads to virus retention and misassembly

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

The hepatitis B virus X gene induces p53-mediated programmed cell death

22 May 2018

1 reference

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A hepatitis B virus mutant with a new hepatocyte nuclear factor 1 binding site emerging in transplant-transmitted fulminant hepatitis B.

22 May 2018

1 reference

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Cytotoxic T cells and viral hepatitis

22 May 2018

1 reference

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Members of the nuclear receptor superfamily regulate transcription from the hepatitis B virus nucleocapsid promoter.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Type, prevalence, and significance of core promoter/enhancer II mutations in hepatitis B viruses from immunosuppressed patients with severe liver disease.

22 May 2018

1 reference

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Two core promotor mutations identified in a hepatitis B virus strain associated with fulminant hepatitis result in enhanced viral replication

22 May 2018

1 reference

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Long-lasting memory T cell responses following self-limited acute hepatitis B

22 May 2018

1 reference

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Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Precore-mediated inhibition of hepatitis B virus progeny DNA synthesis.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Naturally occurring escape mutants of hepatitis B virus with various mutations in the S gene in carriers seropositive for antibody to hepatitis B surface antigen

22 May 2018

1 reference

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Construction of avian hepadnavirus variants with enhanced replication and cytopathicity in primary hepatocytes

22 May 2018

1 reference

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Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen

22 May 2018

1 reference

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Hepatitis B virus (HBV) sequence variation of cytotoxic T lymphocyte epitopes is not common in patients with chronic HBV infection

22 May 2018

1 reference

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The amino-terminal domain of the hepadnaviral P-gene encodes the terminal protein (genome-linked protein) believed to prime reverse transcription

22 May 2018

1 reference

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Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection.

22 May 2018

1 reference

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Is a function of the secreted hepatitis B e antigen to induce immunologic tolerance in utero?

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Chronic active hepatitis with hepatitis B virus DNA and antibody against e antigen in the serum. Disturbed synthesis and secretion of e antigen from hepatocytes due to a point mutation in the precore region

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

A new hepatitis B virus strain in patients with severe anti-HBe positive chronic hepatitis B.

22 May 2018

1 reference

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A hepatitis B virus mutant associated with an epidemic of fulminant hepatitis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Mutations in the precore region of hepatitis B virus DNA in patients with fulminant and severe hepatitis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Fulminant hepatitis B: induction by hepatitis B virus mutants defective in the precore region and incapable of encoding e antigen

22 May 2018

1 reference

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Precore mutant hepatitis B virus infection and liver disease

22 May 2018

1 reference

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Vaccine-induced escape mutant of hepatitis B virus

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

The precore gene of the woodchuck hepatitis virus genome is not essential for viral replication in the natural host

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Loss of the common "A" determinant of hepatitis B surface antigen by a vaccine-induced escape mutant

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Long-term therapy of chronic hepatitis B with lamivudine.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Variant of hepatitis B virus with primary resistance to adefovir

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Analysis of intrahepatic HBV-specific cytotoxic T-cells during and after acute HBV infection in humans.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Oscillating CD8(+) T cell effector functions after antigen recognition in the liver.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

A novel target of hepatitis B virus mutations: splicing of surface RNA.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Hepatitis B virus mutations associated with fulminant hepatitis induce apoptosis in primary Tupaia hepatocytes.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Precore/core promoter mutations and genotypes of hepatitis B virus in chronic hepatitis B patients with fulminant or subfulminant hepatitis

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Long-term safety of lamivudine treatment in patients with chronic hepatitis B.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Inhibitory effect of adefovir and lamivudine on the initiation of hepatitis B virus infection in primary tupaia hepatocytes

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

De Novo Infection in a Renal Transplant Recipient Caused by Novel Mutants of Hepatitis B Virus Despite the Presence of Protective Anti–Hepatitis B Surface Antibody

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Revisiting the cytopathic effect of hepatitis B virus infection

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Hepatitis B virus mutants and fulminant hepatitis B: fitness plus phenotype

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

A dominant hepatitis B virus population defective in virus secretion because of several S-gene mutations from a patient with fulminant hepatitis

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Lamivudine treatment can overcome cytotoxic T-cell hyporesponsiveness in chronic hepatitis B: new perspectives for immune therapy.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Licensed recombinant hepatitis B vaccines protect chimpanzees against infection with the prototype surface gene mutant of hepatitis B virus

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

The pre-S region determines the intracellular localization and appearance of hepatitis B virus

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Competition in vivo between a cytopathic variant and a wild-type duck hepatitis B virus

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

New hepatitis B virus mutant form in a blood donor that is undetectable in several hepatitis B surface antigen screening assays

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Hepatitis B virus S mutants in liver transplant recipients who were reinfected despite hepatitis B immune globulin prophylaxis.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Transmission of a homogenous hepatitis B virus population of A1896-containing strains leading to mild resolving acute hepatitis and seroconversion to hepatitis B e antigen antibodies in an adult

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Pre-S2 defective hepatitis B virus infection in patients with fulminant hepatitis.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Hepatitis B virus envelope variation after transplantation with and without hepatitis B immune globulin prophylaxis

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Coinfection study of precore mutant and wild-type hepatitis B-like virus in ducklings

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Hepatitis B virus strains with mutations in the core promoter in patients with fulminant hepatitis

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Replication of the genome of a hepatitis B-like virus by reverse transcription of an RNA intermediate

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Complex HBV populations with mutations in core promoter, C gene, and pre-S region are associated with development of cirrhosis in long-term renal transplant recipients

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Functional analysis of HBV genomes from patients with fulminant hepatitis

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Incubation phase of acute hepatitis B in man: dynamic of cellular immune mechanisms

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4065880

Breakthrough infections and identification of a viral variant in Gambian children immunized with hepatitis B vaccine

2 November 2018

1 reference

12 December 2020

Variants of two major T cell epitopes within the hepatitis B surface antigen are not recognized by specific T helper cells of vaccinated individuals

1 reference

12 December 2020

Lamivudine as initial treatment for chronic hepatitis B in the United States

1 reference

12 December 2020

Genetic alterations in the gene encoding the major HBsAg: DNA and immunological analysis of recurrent HBsAg derived from monoclonal antibody-treated liver transplant patients

1 reference

12 December 2020

Do T cells "see" the hepatitis B core and e antigens differently?

1 reference

12 December 2020

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

1 reference

12 December 2020

Changes of hepatitis B surface antigen variants in carrier children before and after universal vaccination in taiwan

1 reference

12 December 2020

Identifiers

DOI

10.3748/WJG.V13.I1.82

1 reference

9 May 2018

PMCID

4065880

1 reference

9 May 2018

PubMed ID

17206757

1 reference

9 May 2018