(Q52930336)

9 May 2018

title

The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. (English)

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9 May 2018

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ChEBI release 2020-05-28

3

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9 May 2018

Tatsuya Kaminishi

4

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9 May 2018

Shigeyuki Yokoyama

11

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9 May 2018

Paola Fucini

12

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9 May 2018

Frank Schluenzen

object named as

Frank Schluenzen

1

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author name string

Chie Takemoto

2

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9 May 2018

Joerg M Harms

5

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9 May 2018

Kyoko Hanawa-Suetsugu

6

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9 May 2018

Witold Szaflarski

7

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9 May 2018

Masahito Kawazoe

8

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9 May 2018

Mikako Shirouzu

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9 May 2018

Knud H Nierhaus

10

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9 May 2018

publication date

24 September 2006

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9 May 2018

Nature Structural & Molecular Biology

published in

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9 May 2018

volume

13

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9 May 2018

issue

10

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9 May 2018

page(s)

871-878

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9 May 2018

Expression vectors for quantitating in vivo translational ambiguity: their potential use to analyse frameshifting at the HIV gag-pol junction.

cites work

1 reference

STREPTOMYCIN, SUPPRESSION, AND THE CODE

21 January 2018

1 reference

Resistance of lambda cI translation to antibiotics that inhibit translation initiation

21 January 2018

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Differential inhibition of 30S and 70S translation initiation complexes on leaderless mRNA by kasugamycin

21 January 2018

1 reference

Isolation of kasugamycin resistant mutants in the 16 S ribosomal RNA of Escherichia coli.

21 January 2018

1 reference

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

21 January 2018

1 reference

Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.

21 January 2018

1 reference

Structures of the bacterial ribosome at 3.5 A resolution

21 January 2018

1 reference

Interaction of antibiotics with functional sites in 16S ribosomal RNA

21 January 2018

1 reference

Crystal structure of the ribosome at 5.5 A resolution

21 January 2018

1 reference

Conformational and thermodynamic effects of naturally occurring base methylations in a ribosomal RNA hairpin of Bacillus stearothermophilus.

21 January 2018

1 reference

A carbon-13 nuclear magnetic resonance study of the 3'-terminus of 16S ribosomal RNA of Escherichia coli specifically labeled with carbon-13 in the methylgroups of the m6(2)Am6(2)A sequence

21 January 2018

1 reference

Mutational analysis of the conserved bases C1402 and A1500 in the center of the decoding domain of Escherichia coli 16 S rRNA reveals an important tertiary interaction.

21 January 2018

1 reference

Differential effects of aminoglycosides on cistron-specific initiation of protein synthesis

21 January 2018

1 reference

Differential inhibition of coliphage MS2 protein synthesis by ribosome-directed antibiotics

21 January 2018

1 reference

Unfolding of mRNA secondary structure by the bacterial translation initiation complex

21 January 2018

1 reference

Control of translation by mRNA secondary structure in Escherichia coli. A quantitative analysis of literature data

21 January 2018

1 reference

Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites

21 January 2018

1 reference

Codon-anticodon interaction at the P site is a prerequisite for tRNA interaction with the small ribosomal subunit

21 January 2018

1 reference

Initiation of mRNA translation in prokaryotes

21 January 2018

1 reference

Translation initiation with 70S ribosomes: an alternative pathway for leaderless mRNAs

21 January 2018

1 reference

Evidence for the translation initiation of leaderless mRNAs by the intact 70 S ribosome without its dissociation into subunits in eubacteria.

21 January 2018

1 reference

Interaction of Era with the 30S ribosomal subunit implications for 30S subunit assembly

21 January 2018

1 reference

Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution

21 January 2018

1 reference

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

21 January 2018

1 reference

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

Structural basis for the function of the ribosomal L7/12 stalk in factor binding and GTPase activation

21 January 2018

1 reference

Recognition of cognate transfer RNA by the 30S ribosomal subunit

21 January 2018

1 reference

Chemical studies on kasugamycin. V. The structure of kasugamycin

21 January 2018

1 reference

Translational Operator of mRNA on the Ribosome: How Repressor Proteins Exclude Ribosome Binding

21 January 2018

1 reference

[19] Preparation of functional ribosomal complexes and effect of buffer conditions on tRNA positions observed by cryoelectron microscopy

21 January 2018

1 reference

Increased translational fidelity caused by the antibiotic kasugamycin and ribosomal ambiguity in mutants harbouring the ksgA gene

21 January 2018

1 reference

Inhibition by kasugamycin of initiation complex formation on 30S ribosomes

31 March 2020

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The binding of kasugamycin to the Escherichia coli ribosomes

31 March 2020

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Differential inhibitory effects of antibiotics on the biosynthesis of envelope proteins of Escherichia coli

31 March 2020

1 reference

Mechanism of Kasugamycin Action on Polypeptide Synthesis

31 March 2020

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Parameters for the preparation of Escherichia coli ribosomes and ribosomal subunits active in tRNA binding

31 March 2020

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Inhibition by kasugamycin of protein synthesis in Piricularia oryzae

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Change in methylation of 16S ribosomal RNA associated with mutation to kasugamycin resistance in Escherichia coli

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Mechanism of kasugamycin resistance in Escherichia coli

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NSMB1145

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9 May 2018

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9 May 2018