(Q52931736)

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NOTCH1 mutations associate with low CD20 level in chronic lymphocytic leukemia: evidence for a NOTCH1 mutation-driven epigenetic dysregulation.

scientific article published on 13 July 2015

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19 February 2020

NOTCH1 mutations associate with low CD20 level in chronic lymphocytic leukemia: evidence for a NOTCH1 mutation-driven epigenetic dysregulation (English)

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19 February 2020

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chronic lymphocytic leukemia

1 reference

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Francesca Arruga

3

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19 February 2020

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19 February 2020

Riccardo Bomben

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19 February 2020

Antonella Zucchetto

10

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19 February 2020

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19 February 2020

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19 February 2020

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19 February 2020

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19 February 2020

Dania Benedetti

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19 February 2020

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19 February 2020

Annalisa Chiarenza

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19 February 2020

15

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19 February 2020

Giovanni Del Poeta

19

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19 February 2020

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T Bittolo

2

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19 February 2020

P Bulian

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19 February 2020

B Gizdic

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19 February 2020

F M Rossi

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19 February 2020

G D'Arena

13

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19 February 2020

G Pozzato

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19 February 2020

D Rossi

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19 February 2020

G Gaidano

18

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19 February 2020

S Deaglio

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19 February 2020

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13 July 2015

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19 February 2020

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19 February 2020

30

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19 February 2020

1

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19 February 2020

182-189

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19 February 2020

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

SF3B1 and other novel cancer genes in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Clinical significance of c.7544-7545 delCT NOTCH1 mutation in chronic lymphocytic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Oncogenic and tumor suppressor functions of Notch in cancer: it's NOTCH what you think.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Functions of notch signaling in the immune system: consensus and controversies

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Dynamic binding of RBPJ is determined by Notch signaling status.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

HES and HERP families: multiple effectors of the Notch signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Signalling downstream of activated mammalian Notch

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

The CD49d/CD29 complex is physically and functionally associated with CD38 in B-cell chronic lymphocytic leukemia cells.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Association between molecular lesions and specific B-cell receptor subsets in chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

NOTCH1 mutations in CLL associated with trisomy 12.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

The miR-17∼92 family regulates the response to Toll-like receptor 9 triggering of CLL cells with unmutated IGHV genes.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Escape mechanisms from antibody therapy to lymphoma cells: downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Notch signalling: a simple pathway becomes complex

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Genomic aberrations and survival in chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Chronic lymphocytic leukaemia CD20 expression is dependent on the genetic subtype: a study of quantitative flow cytometry and fluorescent in-situ hybridization in 510 patients

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Down-regulation of CD20 expression in B-cell lymphoma cells after treatment with rituximab-containing combination chemotherapies: its prevalence and clinical significance

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

HDAC inhibitors augment cytotoxic activity of rituximab by upregulating CD20 expression on lymphoma cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

NOTCH1 mutations identify a chronic lymphocytic leukemia patient subset with worse prognosis in the setting of a rituximab-based induction and consolidation treatment.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

A revised NOTCH1 mutation frequency still impacts survival while the allele burden predicts early progression in chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Therapeutic modulation of Notch signalling--are we there yet?

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

The role of histone deacetylases (HDACs) in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2015.182

21 January 2018

E2A is a transcriptional regulator of CD38 expression in chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26165233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immunological profile of B-cell disorders and proposal of a scoring system for the diagnosis of CLL

1 reference

https://pubmed.ncbi.nlm.nih.gov/26165233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL

1 reference

https://pubmed.ncbi.nlm.nih.gov/26165233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26165233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26165233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: further regulation by CD55 and CD59

1 reference

https://pubmed.ncbi.nlm.nih.gov/26165233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26165233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning

1 reference

https://pubmed.ncbi.nlm.nih.gov/26165233

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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