(Q52949738)

9 May 2018

title

Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer. (English)

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9 May 2018

author name string

Arne Scholz

1

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9 May 2018

Sandra Heinze

2

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9 May 2018

Katharina M Detjen

3

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9 May 2018

Michael Peters

4

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9 May 2018

Martina Welzel

5

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9 May 2018

Peter Hauff

6

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9 May 2018

Michael Schirner

7

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9 May 2018

Bertram Wiedenmann

8

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9 May 2018

Stefan Rosewicz

9

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9 May 2018

language of work or name

English

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publication date

1 September 2003

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9 May 2018

published in

Gastroenterology

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9 May 2018

volume

125

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9 May 2018

issue

3

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9 May 2018

page(s)

891-905

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9 May 2018

cites work

Cancer statistics, 1997.

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

No standard treatment is available for advanced pancreatic cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Progress in cancer genetics: lessons from pancreatic cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Interferons as a paradigm for cytokine signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

A road map for those who don't know JAK-STAT

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

STAT proteins and transcriptional responses to extracellular signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Serine phosphorylation of STATs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Suppressors of cytokine signaling: Relevance to gastrointestinal function and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Activation and association of Stat3 with Src in v-Src-transformed cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Overexpression and activation of the tyrosine kinase Src in human pancreatic carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Role of growth factors in pancreatic cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Characterisation of a cell line (LCC-18) from a cultured human neuroendocrine-differentiated colonic carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Overexpression of pRB in human pancreatic carcinoma cells: function in chemotherapy-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Effects of interferon alpha on vascular endothelial growth factor gene transcription and tumor angiogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Molecular mechanism of interferon alfa-mediated growth inhibition in human neuroendocrine tumor cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

STAT proteins: novel molecular targets for cancer drug discovery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Growth factors and cytokines in pancreatic carcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Production of transforming growth factor alpha in human pancreatic cancer cells: evidence for a superagonist autocrine cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Elevated serum interleukin-6 levels in patients with pancreatic cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Interleukin-6 produced by pancreatic carcinoma cells enhances humoral immune responses against tumor cells: a possible event in tumor regression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Interleukin (IL)-6 as a pancreas carcinoma-derived vascular permeability regulator in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

A family of cytokine-inducible inhibitors of signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Hammerhead ribozyme specifically inhibits mutant K-ras mRNA of human pancreatic cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Regulation of Bcl-xL: a little bit of this and a little bit of STAT.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Roles of STAT3 defined by tissue-specific gene targeting

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

DPC4/SMAD4 gene alterations in human cancer, and their functional implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Blocking oncogenic Ras signaling for cancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

STAT3 orchestrates contradictory signals in cytokine-induced G1 to S cell-cycle transition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

STAT3 regulates the growth and immunoglobulin production of BCL(1) B cell lymphoma through control of cell cycle progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

Association between nonsteroidal anti-inflammatory drug use and the incidence of pancreatic cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0016-5085%2803%2901064-3

10.1016/S0016-5085(03)01064-3

7 January 2021

Identifiers

DOI

1 reference

9 May 2018

PubMed ID

12949733

1 reference

9 May 2018