(Q52958600)

9 May 2018

title

Immunological blockade of adipocyte inflammation caused by increased matrix metalloproteinase-cleaved osteopontin in obesity. (English)

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10

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Thomas M Stulnig

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Bianca K Itariu

object named as

Bianca K Itariu

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author name string

Lukas Leitner

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9 May 2018

Karina Schuch

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Alexander Jürets

3

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Maike Keck

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Viktor Grablowitz

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Oskar C Aszmann

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Gerhard Prager

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Günther Staffler

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publication date

16 March 2015

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9 May 2018

published in

Obesity

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volume

23

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issue

4

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page(s)

779-785

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Guidelines for healthy weight

cites work

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Inflammation: the link between insulin resistance, obesity and diabetes

21 January 2018

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From blood monocytes to adipose tissue-resident macrophages: induction of diapedesis by human mature adipocytes.

21 January 2018

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Osteopontin is an activator of human adipose tissue macrophages and directly affects adipocyte function.

21 January 2018

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Osteopontin deficiency protects against obesity-induced hepatic steatosis and attenuates glucose production in mice.

21 January 2018

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Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice

21 January 2018

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Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin).

21 January 2018

1 reference

An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma.

21 January 2018

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Adipocyte produces matrix metalloproteinases 2 and 9: involvement in adipose differentiation

21 January 2018

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Potential role of increased matrix metalloproteinase-2 (MMP2) transcription in impaired adipogenesis in type 2 diabetes mellitus

21 January 2018

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Control of osteopontin signaling and function by post-translational phosphorylation and protein folding

21 January 2018

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Distinct structural requirements for binding of the integrins alphavbeta6, alphavbeta3, alphavbeta5, alpha5beta1 and alpha9beta1 to osteopontin

21 January 2018

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Osteopontin is highly susceptible to cleavage in bovine milk and the proteolytic fragments bind the αVβ₃-integrin receptor

21 January 2018

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Tissue-specific differences in inflammatory infiltrate and matrix metalloproteinase expression in adipose tissue and liver of mice with diet-induced obesity.

21 January 2018

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Matrix metalloproteinases are differentially expressed in adipose tissue during obesity and modulate adipocyte differentiation

21 January 2018

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Osteopontin expression in human and murine obesity: extensive local up-regulation in adipose tissue but minimal systemic alterations.

21 January 2018

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Obesity-associated insulin resistance is correlated to adipose tissue vascular endothelial growth factors and metalloproteinase levels

21 January 2018

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Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes.

21 January 2018

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The differential amino acid requirement within osteopontin in alpha4 and alpha9 integrin-mediated cell binding and migration

21 January 2018

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N-terminal rather than full-length osteopontin or its C-terminal fragment is associated with carotid-plaque inflammation in hypertensive patients

21 January 2018

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Osteopontin is cleaved at multiple sites close to its integrin-binding motifs in milk and is a novel substrate for plasmin and cathepsin D.

21 January 2018

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Polymeric osteopontin employs integrin alpha9beta1 as a receptor and attracts neutrophils by presenting a de novo binding site

21 January 2018

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Osteopontin-stimulated expression of matrix metalloproteinase-9 causes cardiomyopathy in the mdx model of Duchenne muscular dystrophy

21 January 2018

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Osteopontin promotes gastric cancer metastasis by augmenting cell survival and invasion through Akt-mediated HIF-1alpha up-regulation and MMP9 activation

21 January 2018

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Osteopontin: a multifunctional molecule regulating chronic inflammation and vascular disease

21 January 2018

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Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage.

21 January 2018

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

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CC chemokine and CC chemokine receptor profiles in visceral and subcutaneous adipose tissue are altered in human obesity.

21 January 2018

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CCL5 promotes macrophage recruitment and survival in human adipose tissue

21 January 2018

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NF-κB is important for TNF-α-induced lipolysis in human adipocytes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/OBY.21024

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9 May 2018

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9 May 2018