(Q52992155)

English

Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen-driven affinity selection.

scientific article published in October 2005

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scholarly article

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Europe PubMed Central

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6 January 2020

Problems in using statistical analysis of replacement and silent mutations in antibody genes for determining antigen-driven affinity selection (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16162266%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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6 January 2020

author name string

Subrata Sinha

2

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6 January 2020

publication date

1 October 2005

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6 January 2020

1 reference

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6 January 2020

116

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6 January 2020

2

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6 January 2020

172-183

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6 January 2020

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

The molecular basis of somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

The intrinsic hypermutability of antibody heavy and light chain genes decays exponentially

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

The inference of antigen selection on Ig genes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

The role of somatic mutation in determining the affinity of anti-DNA antibodies.

1 reference

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21 January 2018

Evidence for somatic mutation and affinity maturation of diabetes associated human autoantibodies to glutamate decarboxylase

1 reference

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21 January 2018

Memory B cells producing somatically mutated antiphospholipid antibodies are present in healthy individuals

1 reference

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21 January 2018

A systematic analysis of sequences of human antiphospholipid and anti-beta2-glycoprotein I antibodies: the importance of somatic mutations and certain sequence motifs

1 reference

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21 January 2018

Structure-function analysis of a lupus anti-DNA autoantibody: central role of the heavy chain complementarity-determining region 3 Arg in binding of double- and single-stranded DNA.

1 reference

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21 January 2018

Primary malignant lymphoma of the brain: mutation pattern of rearranged immunoglobulin heavy chain gene.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Strong intrinsic biases towards mutation and conservation of bases in human IgVH genes during somatic hypermutation prevent statistical analysis of antigen selection.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Characterization and molecular modeling of a highly stable anti-Hepatitis B surface antigen scFv.

1 reference

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21 January 2018

Intracellular expression of a cloned antibody fragment interferes with hepatitis B virus surface antigen secretion

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Cloning and characterization of cDNAs coding for heavy and light chains of a monoclonal antibody specific for the S antigen of hepatitis B virus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Cloning and sequence analysis of cDNAs encoding the heavy and light chain variable regions of a human monoclonal antibody with specificity for hepatitis B surface antigen.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Development of a cocktail of recombinant-expressed human rabies virus-neutralizing monoclonal antibodies for postexposure prophylaxis of rabies

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

IMGT, the international ImMunoGeneTics database

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

WAM: an improved algorithm for modelling antibodies on the WEB.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Structure and energetics of ligand binding to proteins: Escherichia coli dihydrofolate reductase-trimethoprim, a drug-receptor system.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Low antigen dose favours selection of somatic mutants with hallmarks of antibody affinity maturation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Positive selection on the H3 hemagglutinin gene of human influenza virus A.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

An algorithm for mapping positively selected members of quasispecies-type viruses

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Why are there so few key mutant clones? The influence of stochastic selection and blocking on affinity maturation in the germinal center

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2005.02208.X

21 January 2018

Genes and antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1817819

7 September 2018

The dead-end elimination theorem: mathematical aspects, implementation, optimizations, evaluation, and performance

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7 September 2018

Genealogical evidence for positive selection in the nef gene of HIV-1

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7 September 2018

Clonal evolution of B cells in transformation from low- to high-grade lymphoma

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7 September 2018

Clonal analysis of a human antibody response. III. Nucleotide sequences of monoclonal IgM, IgG, and IgA to rabies virus reveal restricted V kappa gene utilization, junctional V kappa J kappa and V lambda J lambda diversity, and somatic hypermutation

1 reference

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7 September 2018

Myeloma VL and VH gene sequences reveal a complementary imprint of antigen selection in tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1817819

7 September 2018

VH and VL gene analysis in sporadic Burkitt's lymphoma shows somatic hypermutation, intraclonal heterogeneity, and a role for antigen selection

1 reference

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7 September 2018

A human monoclonal antibody with the capacity to neutralize Staphylococcus aureus alpha-toxin.

1 reference

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Modeling and optimization of populations subject to time-dependent mutation

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7 September 2018

Functional properties of isotype-switched immunoglobulin M (IgM) and IgG monoclonal antibodies to Pseudomonas aeruginosa lipopolysaccharide.

1 reference

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7 September 2018

Evaluation of loss and change of specificity resulting from random mutagenesis of an antibody VH region.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1817819

7 September 2018

Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse

1 reference

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7 September 2018

Murine immune response to the Neisseria meningitidis group C capsular polysaccharide. II. Specificity.

1 reference

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7 September 2018

The role of somatic hypermutation in the generation of antibody diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1817819

7 September 2018

Positive Darwinian evolution in human influenza A viruses

1 reference

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7 September 2018

The development of B cells and the B-cell repertoire in the microenvironment of the germinal center

1 reference

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7 September 2018

Analysis of antibodies of known structure suggests a lack of correspondence between the residues in contact with the antigen and those modified by somatic hypermutation

1 reference

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2 November 2018

Mutation analysis of the rearranged immunoglobulin heavy chain genes of marginal zone cell lymphomas indicates an origin from different marginal zone B lymphocyte subsets

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Evidence that amyloidogenic light chains undergo antigen-driven selection

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Identification of specificity-determining residues in antibodies

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30 November 2018

Salivary gland mucosa-associated lymphoid tissue lymphoma immunoglobulin V(H) genes show frequent use of V1-69 with distinctive CDR3 features

1 reference

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Evolution of Ig DNA sequence to target specific base positions within codons for somatic hypermutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16162266

12 December 2020

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Sequence analysis, expression, and paratope characterization of a single-chain Fv fragment for the eukaryote ribosomal P proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16162266

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular histogenesis of posttransplantation lymphoproliferative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/16162266

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inferred from PubMed ID database lookup

Mutational status of IgVH genes consistent with antigen-driven selection but not percent of mutations has prognostic impact in B-cell chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16162266

12 December 2020

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inferred from PubMed ID database lookup

Affinity maturation and hypermutation in a simulation of the humoral immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/16162266

12 December 2020

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inferred from PubMed ID database lookup

Somatic evolution in the immune system: the need for germinal centers for efficient affinity maturation

1 reference

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Harmful somatic mutations: lessons from the dark side

1 reference

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Reconciling repertoire shift with affinity maturation: the role of deleterious mutations

1 reference

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1 reference

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Identifiers

10.1111/J.1365-2567.2005.02208.X

1 reference

Europe PubMed Central

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6 January 2020

0 references

1 reference

Europe PubMed Central

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6 January 2020

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