(Q53010435)

10 May 2018

title

Structure-specific nuclease activity of RAGs is modulated by sequence, length and phase position of flanking double-stranded DNA. (English)

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10 May 2018

author name string

Rupa Kumari

series ordinal

1

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10 May 2018

Sathees C Raghavan

series ordinal

2

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10 May 2018

language of work or name

English

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publication date

14 November 2014

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10 May 2018

published in

FEBS Journal

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10 May 2018

volume

282

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10 May 2018

issue

1

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10 May 2018

page(s)

4-18

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10 May 2018

The RAG proteins and V(D)J recombination: complexes, ends, and transposition

cites work

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

21 January 2018

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Role of recombination activating genes in the generation of antigen receptor diversity and beyond

21 January 2018

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The bounty of RAGs: recombination signal complexes and reaction outcomes

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13121

Molecular analysis of V(D)J recombination

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13121

Mechanistic aspects of lymphoid chromosomal translocations

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13121

Understanding how the V(D)J recombinase catalyzes transesterification: distinctions between DNA cleavage and transposition

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13121

How does DNA break during chromosomal translocations?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

A non-B-DNA structure at the Bcl-2 major breakpoint region is cleaved by the RAG complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Double-strand break formation by the RAG complex at the bcl-2 major breakpoint region and at other non-B DNA structures in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Cytosines, but not purines, determine recombination activating gene (RAG)-induced breaks on heteroduplex DNA structures: implications for genomic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Differential reaction kinetics, cleavage complex formation, and nonamer binding domain dependence dictate the structure-specific and sequence-specific nuclease activity of RAGs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

The structure-specific nicking of small heteroduplexes by the RAG complex: implications for lymphoid chromosomal translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Hairpin coding end opening is mediated by RAG1 and RAG2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

DNA hairpin opening mediated by the RAG1 and RAG2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Sequence and structural basis for chromosomal fragility during translocations in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Both V(D)J coding ends but neither signal end can recombine at the bcl-2 major breakpoint region, and the rejoining is ligase IV dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

DNA cleavage activity of the V(D)J recombination protein RAG1 is autoregulated.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

A non-B DNA can replace heptamer of V(D)J recombination when present along with a nonamer: implications in chromosomal translocations and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Evidence for a triplex DNA conformation at the bcl-2 major breakpoint region of the t(14;18) translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites.

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13121

Hin recombinase bound to DNA: the origin of specificity in major and minor groove interactions

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13121

Mechanisms of programmed DNA lesions and genomic instability in the immune system.

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13121

Chromosomal translocations among the healthy human population: implications in oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Mechanism of fragility at BCL2 gene minor breakpoint cluster region during t(14;18) chromosomal translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Efficiency of nonhomologous DNA end joining varies among somatic tissues, despite similarity in mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

Evidence for Ku70/Ku80 association with full-length RAG1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13121

21 January 2018

Identifiers

DOI

10.1111/FEBS.13121

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10 May 2018

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10 May 2018