(Q53080639)

11 May 2018

title

MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2. (English)

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11 May 2018

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Wen-Ting Liao

1

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11 May 2018

Ya-Ping Ye

2

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11 May 2018

Nian-Jie Zhang

3

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11 May 2018

Ting-Ting Li

4

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11 May 2018

Shu-Yang Wang

5

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11 May 2018

Yan-Mei Cui

6

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11 May 2018

Lu Qi

7

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11 May 2018

Ping Wu

8

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11 May 2018

Hong-Li Jiao

9

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11 May 2018

Yi-Jun Xie

10

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11 May 2018

Chi Zhang

11

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11 May 2018

Jun-Xian Wang

12

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11 May 2018

Yan-Qing Ding

13

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11 May 2018

publication date

1 March 2014

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11 May 2018

published in

Journal of Pathology

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11 May 2018

volume

232

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11 May 2018

page(s)

415-427

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11 May 2018

issue

4

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11 May 2018

cites work

Cancer statistics, 2013

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MicroRNAs in colorectal cancer: translation of molecular biology into clinical application

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MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer

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miR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4.

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miR-30a suppresses cell migration and invasion through downregulation of PIK3CD in colorectal carcinoma

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MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL.

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Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene

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MicroRNA-384-5p regulates ischemia-induced cardioprotection by targeting phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (PI3K p110δ).

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Identification of miR-30d as a novel prognostic maker of prostate cancer

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MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop

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The colorectal microRNAome

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MicroRNAs and colon and rectal cancer: differential expression by tumor location and subtype

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MicroRNA profiling differentiates colorectal cancer according to KRAS status.

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

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Amplification and up-regulation of microRNA-30b in oral squamous cell cancers.

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Amplification and overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma

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miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis.

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Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells

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A MicroRNA expression profile defining the invasive bladder tumor phenotype

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Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of Tongue

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Bcl-2 overexpression in PhIP-induced colon tumors: cloning of the rat Bcl-2 promoter and characterization of a pathway involving beta-catenin, c-Myc and E2F1

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A microRNA expression signature of human solid tumors defines cancer gene targets

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MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation

21 January 2018

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HER2, TOP2A, CCND1, EGFR and C-MYC oncogene amplification in colorectal cancer

21 January 2018

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8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy

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Defensins and the dynamic genome: what we can learn from structural variation at human chromosome band 8p23.1.

21 January 2018

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Copy number polymorphism and expression level variation of the human alpha-defensin genes DEFA1 and DEFA3

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21 January 2018

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21 January 2018

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Activity of any class IA PI3K isoform can sustain cell proliferation and survival.

21 January 2018

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Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells

21 January 2018

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Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

21 January 2018

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Prevalence of ras gene mutations in human colorectal cancers

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.4309

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11 May 2018

PubMed ID

24293274

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11 May 2018